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作 者:刘梅[1] 施有为[1] 张晓红[1,2] 周炳凤[1] 刘江潮[1] 殷丽琼[1] 周根东[1]
机构地区:[1]合肥市第一人民医院心内科,安徽合肥230036 [2]合肥市第一人民医院超声心动图室
出 处:《心血管康复医学杂志》2011年第4期382-384,共3页Chinese Journal of Cardiovascular Rehabilitation Medicine
摘 要:目的:观察冠心病患者的颈动脉超声检查的特征,探索冠心病病情严重程度与颈动脉超声检查的关系。方法:选择在心内科同期住院的102例冠心病患者,其中心肌梗死(MI)患者37例,非MI患者65例,另选58例非冠心病患者作为正常对照组。测定颈动脉超声图像,血流动力学指标,血脂、血糖等生化指标,并进行统计学分析。结果:颈动脉超声显示,颈动脉内膜中层厚度在冠心病非MI组[(0.99±0.18)mm],MI组[(0.99±0.22)mm]明显大于正常对照组[(0.78±0.11)mm],P<0.05,颈总动脉最大流速冠心病非MI组[(71.34±19.76)cm/s],MI组[(78.92±20.61)cm/s]明显高于正常对照组[(67.38±14.35)cm/s],P<0.05。冠心病非MI组斑块发生率为69.2%,MI组为62.2%,明显高于正常对照组(36.2%,P均<0.01)。Pearson相关分析显示颈动脉内膜中层厚度与总胆固醇、低密度脂蛋白-胆固醇、甘油三酯水平呈显著正相关(标准化回归系数0.460~0.862,P均<0.001)。结论:颈动脉超声不仅可间接评价冠心病患者,且颈动脉内膜中层的厚度与血脂异常显著相关。Objective:To observe characteristics of carotid artery ultrasonogram in patients with coronary heart disease(CHD) and explore the relationship between carotid artery ultrasonogram and severity of CHD.Methods:A total of 102 CHD patients admitted in our department were enrolled,including 37 cases with myocardial infarction(MI group) and 65 non-MI cases(CHD non-MI group).Another 58 non-CHD patients were enrolled as normal control group.Carotid artery ultrasonogram,hemodynamic indexes,and biochemical indexes such as blood lipid and blood glucose of the patients were measured and statistically analyzed.Results:Carotid artery ultrasonogram indicated that carotid intima-media thickness of CHD non-MI group [(0.99±0.18)mm] and MI group [(0.99±0.22)mm] significantly increased compared with that of control group [(0.78±0.11) mm],P〈0.05.Carotid artery peak velocities of CHD non-MI group [(71.34±19.76)cm/s] and MI group [(78.92±20.61)cm/s] were significantly higher than that of control group [(67.38±14.35) cm/s],P〈0.05.Incidence rates of carotid plaque of CHD non-MI group(69.2%) and MI group(62.2%) were significantly higher than that of control group(36.2%,P〈0.01 both).Pearson correlation analysis indicated that carotid intima-media thickness is positively correlated with levels of total cholesterd,low density lipoprotein-chdsterd and triglyceride(standardized regression coefficient 0.460~0.862,P〈0.001 all).Conclusion:Carotid artery ultrasonography could indirectly evaluate coronary heart disease.Carotid intima-media thickness is significantly correlated with dyslipidemia.
分 类 号:R541.4[医药卫生—心血管疾病]
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