瑞芬太尼复合七氟醚在颅内动脉瘤栓塞术中的临床观察  

Clinical study of remifentanil combined with sevoflurane in intracranial aneurysm embolization

作　　者：皮名芳[1] 陈春[1] 侯俊[1] 唐万英[1] 王锋[1] 

机构地区：[1]三峡大学第一临床医学院宜昌市中心人民医院麻醉科,湖北宜昌443003

出　　处：《四川医学》2011年第8期1250-1252,共3页Sichuan Medical Journal

摘　　要：目的观察瑞芬太尼合复七氟醚在颅内动脉瘤栓塞术中的临床效果。方法选择择期行颅内动脉瘤栓塞术患者42例,所有患者全麻诱导方法相同,麻醉维持采用持续泵注瑞芬太尼0.05～0.1μg/(kg.min)、顺式阿曲库胺0.1mg/(kg.h)持续吸入七氟醚(1.5%～2%),根据生命体征调整瑞芬太尼泵注速度和七氟醚吸入浓度。记录麻醉诱导前1min(T1)、诱导后1min(T2)、插管时(T3)、置弹簧圈(T4)、手术结束(T5)和拔管时(T6)的血压、心率变化及清醒拔管时间。结果在停药后30min内均能清醒拔管,与T1的血压、心率相比,T2和T4有所降低(P<0.05),但均在正常范围内;T6血压、心率均有一过性升高(P<0.05)。结论瑞芬太尼复合七氟醚应用于颅内动脉瘤栓塞术中可维持血流动力学稳定,术后苏醒迅速、平稳,是一种安全有效的麻醉方法。Objeceive To evaluate the clinical efficacy of remifentanil combined with sevoflurane in intracranial aneurysm embolization.Methods 42 patients scheduled for intracranial aneurysm embolization were undergone the same induction.All patients were continuously infused with remifentanil,cisatracurium and inhalated sevoflurane during operation.According to life indexes adjusted the infusing speed of remifentanil and inhalation of sevoflurane.The blood pressure and heart rate at 1 min before induction、1 min after induction、intubation、embolization、after operation and extubation were recorded.the time of awaken were recorded too.Results The blood pressure and heart rate after induction and during operation were decreased than before general anesthesia induction（P0.05）,but in normal range.All patients were extubated and became conscious 30 min after discontinuation of the drugs,the blood pressure and pulse rate were transiently increased during extubation（P0.05）.Conclusion Remifentanil combined with sevoflurane is an safe and effctive anesthesia method in intracranial aneurysm embolization,with stable hemodynamic paraments during operation and rapid recovery.

关 键 词：瑞芬太尼 七氟醚 颅内动脉瘤 栓塞 

分 类 号：R614[医药卫生—麻醉学]