槲皮素对免疫低下小鼠体液免疫功能的影响  

Effect of Quercetin on Humoral Immunity Function in Immunosuppressive Mice

作　　者：蒋蕊[1] 考书娟 徐小娟[1] 徐德武[1] 

机构地区：[1]青岛农业大学生物科学学院,山东青岛266109 [2]山东莱阳春雪食品有限公司

出　　处：《青岛农业大学学报（自然科学版）》2011年第2期118-120,125,共4页Journal of Qingdao Agricultural University(Natural Science)

摘　　要：本试验探讨了不同剂量槲皮素对免疫低下小鼠体液免疫功能的影响。通过氢化可的松或环磷酰胺建立免疫抑制小鼠模型,灌胃不同剂量的槲皮素。10d后测定免疫器官指数、脾脏抗体形成细胞和血清溶血素含量。结果表明,槲皮素高、中剂量组小鼠免疫器官指数、抗体形成细胞OD值及血清溶血素HC50明显高于模型组(P<0.05)。The effect of quercetin on humoral immunity function in immunosuppressive mice was investigated in this paper. The model of immune suppression was established by administration with hydrocortisone and cyclophosphamide. The experiment groups were fed with quercetin in different concentrations. Then 10 days later, the immune organ index, spleen plaque forming cell （PFC） and serum hemolysin were detected. The results showed, as compared with those of model group, immune organ index, optical density （OD） of plaque forming cell（PFC） and serum hemolysin were significantly increased in high and medium groups（ P 〈0.05） respectively.

关 键 词：槲皮素 小鼠 体液免疫 抗体形成细胞 

分 类 号：S852.43[农业科学—基础兽医学]