血清降钙素原在儿科呼吸道感染中的临床意义  

Clinical significance of serum procalcitonin in pediatric respiratory infections

作　　者：易丽[1] 王毅[1] 孙朝文[1] 金成鹏[2] 

机构地区：[1]湖北民族学院科技学院,湖北恩施445000 [2]湖北民族学院医学院,湖北恩施445000

出　　处：《中华肺部疾病杂志（电子版）》2011年第3期61-63,共3页Chinese Journal of Lung Diseases(Electronic Edition)

摘　　要：目的分析血清降钙素原(PCT)检测在儿科呼吸道感染中的临床意义。方法选择2009年1月至2011月3月我院儿科住院确诊有感染的119例患儿,随机分为细菌感染组(A)、病毒感染组(B)及非细菌感染组(C),比较各组患儿PCT、C-反应蛋白(CRP)水平,观察患儿血PCT、中性粒细胞比值(%)(NGR%)的水平及使用抗生素药物的治疗效果。结果 A组患儿PCT阳性率44.16%(34/77)明显高于其它两组(P<0.05),PCT检测诊断儿科呼吸道感染明显优于CRP,对患儿(尤其是早产儿)呼吸道感染的早期诊断有较强特异性。结论 PCT是诊断临床儿科呼吸道感染性疾病的重要生化指标,其特异性大于CRP,其结果对于指导儿科临床合理用药有重要意义。Objective To analyse the clinical significance of serum procalcitonin （PCT） testing in pediatric respiratiory infectious diseases. Methods Collection and analysis of Jan. 2009- Jan. 2011 through March Xianning County People＇s Hospital pediatric inpatient diagnosis of infection of 119 patients were randomly assigned to bacterial infection （A）, viral infection （B） and non- bacterial infection （ C）, comparing the group of serum procalcitonin, C-reactive protein （CRP） levels, observed serum procalcitonin, neutrophile granulocyte rate （NGR%） level and the use of antimicrobial drugs treatment. Results A group of serum proealcitonin positive rate 44.16% （34/ 77 ） was significantly higher than that of the other two groups （ P 〈 0.05 ） , showed serum procalcitonin testing and diagnosis of respiratory infection better than pediatric C-reactive protein, the chil- dren （especially in premature children） early diagnosis of respiratory infection had a strong specific- ity. Conclusion Serum calcitonin was originally a clinical diagnosis of pediatric respiratory infections of the important biochemical indicator of specificity than CRP, the resuhs for rational drug guide pediatric clinical significance was even more important.

关 键 词：上呼吸道感染 病毒性肺炎 血清降钙素原 儿科 临床意义 

分 类 号：R562[医药卫生—呼吸系统]