预防性抗感染治疗胎膜早破的临床研究  

CLINICAL STUDY OF PROPHYLACTIC ANTI-INFECTION IN TREATMENT OF PREMATURE RUPTURE OF MEMBRANES

作　　者：翁清燕[1] 

机构地区：[1]海南省中医院妇产科,海口570203

出　　处：《现代预防医学》2011年第17期3439-3440,共2页Modern Preventive Medicine

摘　　要：[目的]探讨预防性使用抗生素对胎膜早破患者的母儿的预后情况。[方法]回顾性分析2009年12月～2010年7月收治在海南省中医院妇产科住院48例胎膜早破患者的临床资料,遵照随机原则分为两组,A组24例采用预防性抗生素治疗,B组24例不接受药物治疗。[结果]A组的剖宫产率明显低于B组,A组的产妇绒毛膜炎率、产褥感染率明显低于B组,且A组新生儿患吸入性肺炎、胎儿窘迫率均明显低于B组,组间差异有统计学意义(P﹤0.05)。[结论]预防性抗感染治疗胎膜早破,可以降低宫内感染,降低产妇及新生儿的感染机率,值得临床推广应用。[Objective]To evaluate the prognosis of maternal and children premature rupture of membranes with prophylactic use of antibiotics.[Methods]A retrospective analysis was carried out to analyze the clinical data of 48 patients with premature rupture of membranes admitted to Hospital in Obstetrics and Gynecology Hospital of Hainan Province from December 2009-July 2010,in accordance with the principles,the patients were randomly divided into two groups.A group of 24 patients was given with prophylactic antibiotics treatment,B group of 24 patients did not receive drug treatment.[Results]The cesarean section rate in A group was significantly lower than B group,the rate of maternal chorioamnionitis,puerperal infection in A group were significantly lower than the B group,and the rates of newborns suffering from aspiration pneumonia and fetal distress in A group were significantly lower in B group,the difference was significant（P﹤0.05）.[Conclusion]The prophylactic anti-infective therapy for premature rupture of membranes is effective,intrauterine infection,maternal and neonatal infection rates can be reduced,which is worthy of clinical application.

关 键 词：胎膜早破 宫内感染 预防感染治疗 

分 类 号：R714.433[医药卫生—妇产科学]