乐山市美沙酮门诊吸毒人群HIV、HCV、梅毒和HSV-2感染状况调查分析  

INVESTIGATION AND ANALYSIS OF INFECTION WITH HIV,HCV,SYPHILIS AND HSV-2 FOR METHADONE DRUG USERS IN LESHAN CITY

作　　者：牟怀德[1] 陈霞[1] 吴薇[1] 刘昕亮[1] 谢应国[1] 李娜[1] 

机构地区：[1]四川省乐山市疾病预防控制中心,乐山614000

出　　处：《现代预防医学》2011年第17期3550-3552,共3页Modern Preventive Medicine

基　　金：国家科技重大专项课题:重点人群减少艾滋病感染预防技术研究(2008ZX10001-016)课题分题一;"减少吸毒人群感染HIV和阻断已经感染HIV的吸毒者经性传播HIV预防干预研究"基线调查内容之一

摘　　要：[目的]了解乐山市美沙酮门诊吸毒人群HIV、HCV、梅毒和HSV-2感染状况。[方法]采集乐山市3个区市(县)的美沙酮门诊618名吸毒人员的静脉血进行HIV、HCV、梅毒以及HSV-2血清抗体检测,并对检测结果进行分析。[结果]618名吸毒人员HIV抗体阳性率为10.84%,HCV抗体阳性率为71.84%,梅毒抗体阳性率为4.85%;3个美沙酮门诊吸毒人员HIV抗体阳性率以及HCV抗体阳性率差异有统计学意义(χ2=9.43,P=0.01;χ2=29.75,P=0.00);各年龄段间HCV抗体阳性率差异有统计学意义(χ2=5.23,P=0.00);HIV/HCV合并感染率为5.18%、HIV/HCV/梅毒合并感染率为0.16%、HCV/梅毒合并感染率为3.56%。67例艾滋病感染者HSV-2抗体阳性率为61.19%,HIV/HCV/梅毒/HSV-2疱疹合并感染率为1.49%,HIV/HCV/HSV-2疱疹合并感染率为52.24%。[结论]乐山市美沙酮门诊吸毒人群中HIV、HCV、梅毒以及HSV-2感染率较高,合并感染现象严重,应积极开展健康教育并采取针对性的干预措施。[Objective]To investigation the HIV,HCV,syphilis and HSV-2 infection of methadone drug users in Leshan city.[Methods]Collected 618 methadone drug users＇ blood in three cities and counties to test HIV,HCV,syphilis and HSV-2 antibody,and analysed the test results.[Results]The positive rate of HIV antibody of 618 drug users was 10.84%,positive rate HCV antibody was 71.84%,positive rate of syphilis antibody was 4.85%;positive rates of HIV antibody and HCV antibody in three methadone drug users were significantly different（χ2 = 9.43,P = 0.01;χ2 = 29.75,P = 0.00）;the positive rates of HCV antibody in all age groups were significantly different（χ2 = 5.23,P = 0.00）;the combined infection rate of HIV/HCV was 5.18%,combined infection rate of HIV/HCV/syphilis 0.16%,the combined infection rate of HCV/syphilis 3.56%.The positive rate of HSV-2 antibody in 67 cases of HIV infection was 61.19%,the combined infection rate of HIV/HCV/syphilis/HSV-2 herpes was 1.49%,the combined infection rate of HIV/HCV/HSV-2 herpes was 52.24%.[Conclusion]The infection rates of HIV,HCV,syphilis and HSV-2 in methadone drug users are higher,and infections are serious in Leshan city.We should actively carry out health education and take appropriate intervention measures.

关 键 词：美沙酮 吸毒人群 HIV HCV 梅毒 HSV-2 合并感染 

分 类 号：R195[医药卫生—卫生统计学]