肺结核病患者漏服药情况分析  

Analysis on adherence during treatment for pulmonary tuberculosis

作　　者：王群[1] 王伟[1] 严非[1] 成诗明[2] 王倩倩[1] 武桂英[1] 万利亚[2] 

机构地区：[1]复旦大学公共卫生学院公共卫生安全教育部重点实验室,上海200032 [2]中国疾病预防控制中心结核病预防控制中心

出　　处：《中国预防医学杂志》2011年第8期658-661,共4页Chinese Preventive Medicine

基　　金：全球基金项目;中国疾病预防控制中心结核病控制中心组织-"DOTs质量影响因素与评价"(TB07-018)

摘　　要：目的了解肺结核病患者漏服药情况及其影响因素,为促进患者规范治疗提供支持。方法 根据地理位置和经济水平,从全国东部、中部及西部6省抽取12个县共计622例肺结核病患者,使用自编问卷对结核病患者漏服药情况及其影响因素进行询问调查,采用SPSS软件进行描述性分析以及因素分析。结果在治疗过程中有15.3%(95例)的患者发生过漏服药,漏服主要原因为忘记,其次分别为药物不良反应、工作忙、经济困难等。影响患者漏服药的主要因素为性别、患者对规范服药是否是治疗结核病的关键措施和按时服药与肺结核病治疗关系的看法,以及如果发生不良反应是否立即停药的态度。结论 采取多种应对药物不良反应的措施,同时因人制宜开展健康教育和健康促进活动,把握DOTS策略内涵,采用综合措施促进病人规则服药。Objective To analyze factors associated with adherence during treatment for pulmonary tuberculosis（TB） and provide suggestions for improving the efficiencies of treatment.Methods Twelve counties were randomly selected from 6 provinces,which were located in eastern,central and western China.A total of 622 TB patients joined the study of questionnaire survey.The data were analyzed with descriptive epidemiology by SPSS software.Results During treatment,15.27%（95/622） of patients missed at least one dose of medication.Main reasons reported for non-adherence were forgetting to take medicine（51.58%）,side effects（24.21%）,busy with work（9.47%） and economic difficulties（5.26%）,etc.Factors associated with non-adherence were gender,awareness of the importance of medication adherence for tuberculosis treatment and attitude towards the side effects of medication.Conclusion Multiple measures should be taken to efficiently manage the side effects of medication.Comprehensive health education and health promotion activities should be also helpful in improving treatment adherence.

关 键 词：肺结核 漏服药 患者 

分 类 号：R521[医药卫生—内科学]