心功能不全患者血清脑钠素、C反应蛋白、一氧化氮的浓度变化  

The brain natriuretic peptide, C-reactive protein and nitric oxide concentrations in patients with cardiac dysfunctionThe brain natriuretic peptide, C-reactive protein and nitric oxide concentrations in patients with cardiac dysfunction

作　　者：龙运玲 陆海灵 彭湘南 陈世凤[1] 邓少伦 陈龙军[1] 

机构地区：[1]北海市卫生学校附属医院内三科,广西壮族自治区536100

出　　处：《中国心血管病研究》2011年第8期613-614,共2页Chinese Journal of Cardiovascular Research

摘　　要：目的研究脑钠素（BNP）、C反应蛋白（CRP）、一氧化氮（NO）在心功能不全（HF）时的浓度变化。方法测定人选的30例心功能不全患者的BNP、CRP和NO含量，并与正常对照组作对比。结果不同分级的心功能不全患者血清BNP、CRP和NO浓度变化有显著性差异（多元方差分析，F=8．931（a），P=0．01）。结论血清BNP、CRP和NO浓度在心功能不全时变化差异显著，可作为心功能不全时的监测指标。Objective To study the concentrations of brain natriuretic peptide （BNP）, C-reactive protein （CRP）, nitlic oxide （NO） in patients with cardiac insufficiency. Methods Brain natriuretic peptide, C-reactive protein and nitric oxide were measured in 30 cases of patients with heart failure and 30 normal patients as comparison. Results The concentration of serum BNP, CRP and NO was significantly different in different classification of heart failure（multivariate analysis of variance, F=8.931（a）, P=0.001 ）. Conclusion The concentration of serum BNP, CRP and NO in patients with cardiac insufficiency can be used as indicators for degree of heart failure.

关 键 词：脑钠素 C反应蛋白 一氧化氮 慢性心功能不全 

分 类 号：R541[医药卫生—心血管疾病]