新编汉语文字流畅性测验在健康青年人群中的试用  

A novel Chinese letter fluency test applied to healthy youth

作　　者：宋明桥[1] 郑文旭[1] 李晓红[1] 刘萍[1] 

机构地区：[1]大连市友谊医院神经内科,大连116001

出　　处：《中华行为医学与脑科学杂志》2011年第8期734-736,共3页Chinese Journal of Behavioral Medicine and Brain Science

摘　　要：目的文字流畅性测验是评估人脑前额叶皮质（PFC）认知功能的重要神经心理学测验之一，但缺乏成熟的汉语版本，尝试编制一种类似于英语版本的汉语文字流畅性测验，为研究以汉语为母语的人群的PFC功能提供一个有效的手段。方法选择健康的19—33岁以汉语为母语的被试30名（男13名，女17名），在完成新编汉语文字流畅性测验的同时用近红外光学成像技术检测对PFC的激活作用，其中部分人完成了三种不同的汉语文字流畅性测验和分类流畅性测验。结果提示音节说词语的汉语文字流畅性测验在60s内的平均成绩为（12．8±4．7）个，在位于PFC的13个通道中有12个通道测验中的[oxy—Hb]相对值显著高于测验前及测验结束后（P〈0．05）。结论新编制的提示音节说词语的汉语文字流畅性测验与英语版本在形式上近似，并有客观证据证明其能有效激活人脑PFC的神经活动，能作为一种测量PFC功能的神经心理学测验应用于以汉语为母语的人群。Objective Letter fluency test is one of the important neuropsychological tests which can examine the cognitive function of the prefrontal cortex （PFC） of human brain. However,there is no successful Chinese version. This research is trying to develop a Chinese letter fluency test similar to the English version,and to provide an effective approach to investigate the function of the PFC of the native Chinese speakers. Methods Thirty 19 -33 years old healthy native Chinese speakers were chosen （13 men and 17 women）. The near-infrared spectroscopy was used to observe the activation of the PFC while the participants carried out the Chinese letter fluency tests. Some of the participants carried out three kinds of letter fluency tests and category fluency test. Results The average score of the Chinese letter fluency test using syllable cue in 60 s was 12.8 ± 4.7. The relative value of [ oxy-Hb] in 12 channels of 13 ones located in the PFC during carrying out the test was higher than before and after the test significantly （P〈 0. 05 ）. Conclusion The novel Chinese letter flueney test using syllable cue is similar to the English version formally. The objective evidence shows that it can activate neural activity located in the PFC of human brain,and can be applied to the native Chinese speakers as a neuropsychological test investigating the function of the PFC.

关 键 词：文字流畅性测验 汉语 前额叶皮质 近红外光学成像技术 

分 类 号：R338[医药卫生—人体生理学]