心肌酶谱与心肌损伤标志物在急性心肌梗死诊断中的价值  

APPLICATION OF MYOCARDIAL ZYMOGRAM AND CARDIAC MARKERS TROPONIN I IN DIAGNOSIS OF AMI

作　　者：王喜栋[1] 赵捷[1] 张晋霞[1] 张琳[1] 

机构地区：[1]河北医科大学第二医院检验科,河北石家庄050000

出　　处：《河北医科大学学报》2011年第8期913-915,共3页Journal of Hebei Medical University

摘　　要：目的评价心肌酶谱与心肌损伤标志物肌钙蛋白I(cardiac troponin I,cTnI)在急性心肌梗死(acutemyocardial infarction,AMI)发病早期升高的幅度与在AMI诊断中的动态应用价值。方法对130例AMI患者进行心肌损伤标志物cTnI和心肌酶谱在时间窗口的比较。结果 cTnI在AMI发病早期升高的幅度较心肌酶谱显著,AMI后4h内患者血清中cTnI及肌酸激酶同工酶开始升高,12～24h各项指标达高峰。结论联合检测血清cTnI及心肌酶谱对AMI的早期诊断具有重要的临床价值。Objective To evaluate the dynamic application value of myocardial zymogram and cardiac markers troponin I （cTnI）. In the early diagnosis of acute myocardial infarction （AMI）, by detecting their increasing level and time window. Methods A total of 130 patients with AMI were chosen by random and their myocardial zymogram and cardiac markers troponin I were tested, then their time window were compared. Results The increasing level of cardiac markers cTnI was more remarkable than myocardial zymogram in the early AMI. Serum cTnI and creatine kinase - MB （CK - MB ） began to increase 4 hours after AMI and reached their peaks 12 to 24 hours after AMI. Conclusion serum cTnI and myocardial enzyme simultaneously have important clinical value on the early AMI. Detection of diagnosis of

关 键 词：心肌梗死 肌钙蛋白I 诊断 

分 类 号：R542.22[医药卫生—心血管疾病]