重度阻塞性睡眠呼吸暂停低通气综合征患者鼻通气状态的客观评估  

Study of acoustic rhinometry and rhinomanometry for severe obstructive sleep apnea-hypopnea syndrome

作　　者：陈曦[1] 宋建涛[2] 陈东兰[1] 孙建军[1] 

机构地区：[1]海军总医院耳鼻咽喉头颈外科,北京100048 [2]解放军第474医院耳鼻咽喉头颈外科

出　　处：《临床耳鼻咽喉头颈外科杂志》2011年第17期780-782,共3页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:应用鼻声反射和鼻阻力测量对重度阻塞性睡眠呼吸暂停低通气综合征(sOSAHS)患者的鼻腔状况进行客观评估。方法:39例正常成年男性为A组,65例sOSAHS患者分为B组(BMI<28)和C组(BMI≥28)。分别测量单侧鼻腔第1狭窄面积、单侧鼻腔第2狭窄面积、单侧鼻腔最小截面积、单侧0～5cm、2～5cm鼻腔容积、单侧吸气阻力、单侧呼气阻力及鼻气道总阻力(TRins、TRexp),将各组间参数进行比较,并与PSG结果进行相关性分析。结果:B组的鼻阻力值明显高于其他2组(P<0.05),其余各参数组间差异无统计学意义(均P>0.05)。B组的TRins、TRexp均与呼吸暂停低通气指数呈正相关(r=0.402、0.401,均P<0.05)。结论:鼻阻力增高可能是非肥胖sOSAHS患者的发病因素之一。Objective：To study the relationship between nasal airway function and severe obstructive sleep apnea-hypopnea syndrome（sOSAHS）.Method：One hundred and four cases were divided into 3 groups：group A was 39 normal adult men,group B was 25 nonobese patients with sOSAHS（BMI28）,groups C was 40 obese patients with sOSAHS（BMI≥28）.Acoustic rhinometry and rhinomanometer was used to acquire unilateral area of first constriction,unilateral area of second of constriction,unilateral minimum cross-sectional area,unilateral nasal volume 0-5 cm,2-5 cm,the effective unilateral and total nasal resistances in inspiration,expiration at 150 Pa（URins,URexp,TRins,TRexp）.Result：Nasal resistance were significantly higher in the group B compared to the group A and group C（P0.05）.Among the group B,but not the group A and group B,we found significant correlations between TRins,TRexp and apnea hypopnea index（r=0.402,0.401,P0.05）.Conclusion：Nasal resistance is an important factor for nonobese patients with sOSAHS.

关 键 词：鼻声反射 睡眠呼吸暂停低通气综合征 阻塞性 

分 类 号：R765[医药卫生—耳鼻咽喉科]