女性15d头低位卧床实验的组织实施与医学监督  

15 d Head-down Bed Rest of Female Subjects:Practice Overview and Medical Monitoring

作　　者：王林杰[1] 张丽芬 李志利[1] 杨鸿慧[1] 王惠娟[1] 陈文娟[1] 唐国华[1] 王峻[1] 周湘杰 窦跃龙 李莹辉[1] 白延强[1] 

机构地区：[1]中国航天员科研训练中心,航天医学基础与应用国家重点实验室,北京100094 [2]北京航天城门诊部,北京100094

出　　处：《航天医学与医学工程》2011年第4期235-240,共6页Space Medicine & Medical Engineering

基　　金：中国航天医学工程预先研究项目(2008SY5406001)

摘　　要：头低位卧床实验(HDBR)是弥补在轨飞行资源限制的重要地面模拟途径。女性头低位卧床实验是探索我国女性航天员参与航天飞行任务防护方法的重要平台。中国航天员中心组织实施了女性15 d头低位卧床实验,用于评价、比较和改进失重生理效应的防护方法。本文介绍了实验概况,志愿者的选拔情况,卧床实验控制、测试项目和测试时间等。卧床过程中志愿者心率降低,卧床后期舒张压降低,卧床期间静摄水量与卧床前后基本持平。卧床实验的多项结果在本刊的系列文章中给出。本文中的数据是本刊其他关于心血管和肌肉系统文章的基本背景。营养供给、基本认知功能和口腔相关研究结果是成功组织本实验和非靶研究系统的结果。Head-down Bed Rest（HDBR） experiment is an important ground-based analog to make up for the limited resources aboard space station for human research.And female HDBR experiment develops as an primary platform to explore the countermeasures for female astronaut.Astronaut Center of China（ACC） organized the 15 d HDBR experiment of female subjects to evaluate,compare and refine female countermeasure in weightlessness.This paper serves as an overview and describes the experiment control,test item,test time points,etc.Detailed results form multiple-disciplines are presented in a series of reports.Heart rates（HR） decreased during bed rest and diastolic pressure（DSP） dropped at the later period of bed rest.The water balance during bed rest was at the same level as that in pre-and post-bed rest.the data presented in this paper served as a context in which to view the data presented in manuscripts about cardiovascular and muscle system changes.The dietary support,basic cognitive function and stomatology information regarding those aspects of implementing bed rest studies successfully and results from non-targeted system.

关 键 词：模拟失重 头低位卧床 生理效应 对抗措施 

分 类 号：R852.22[医药卫生—航空、航天与航海医学]