纳洛酮联合酚妥拉明治疗肺性脑病30例临床疗效观察  

The Clinical Effectiveness Observation of Administration of Naloxone Together with Phentolamine in 30 Patients with Pulmonary Encephalopathy

作　　者：聂丹丹[1] 邱立志[1] 

机构地区：[1]四川省科学城医院,四川绵阳621900

出　　处：《川北医学院学报》2011年第4期325-327,共3页Journal of North Sichuan Medical College

摘　　要：目的:观察总结纳洛酮与酚妥拉明联用治疗肺性脑病的疗效。方法:对30例确诊为肺性脑病的患者作为治疗组给予纳洛酮与酚妥拉明联合静滴治疗,观察其治疗后的意识及血气分析变化,并设30例肺性脑病患者作为常规治疗组做对照观察。结果:30例经纳洛酮与酚妥拉明联合治疗的肺性脑病的意识改善时间比对照组明显缩短,意识转清率也比对照组明显提高,血气分析比对照组明显改善。结论:纳洛酮与酚妥拉明联用对肺性脑病有明显的促醒作用,能改善患者的临床症状和血气分析指标。Objective：To observe and summarize the effectiveness of administration of Naloxone together with Phentolamine in patients with pulmonary encephalopathy.Methods：60 cases of pulmonary encephalopathy were divided into treatment group（Naloxone ＋ Phentolamine,30 cases） and control group（routine treatment,30 cases）.The changes of awareness,PaO2 and PaCO2 were compared between treatment and control group after treatment.Results：The total effective power（the leading time of awareness improvement,the percentage of clear awareness and the improvement of PaO2 and PaCO2） in treatment group were superior to those in control group.Conclusion：The use of Naloxone in combination with Phentolamine achieved better results in the improvement of awareness,PaO2 PaCO2 and clinical symptom in cases with pulmonary encephalopathy.

关 键 词：肺性脑病 纳洛酮 酚妥拉明 

分 类 号：R563.19[医药卫生—呼吸系统]