“罗布人后裔”特定人群的生理特征调查  

Investigation on physiological characteristics in "offspring of Lop Nor people"

作　　者：玛依拉·吾甫尔[1] 穆叶赛·尼加提[2] 阿木提·司马义[2] 韩伟[3] 李峰[3] 阿布力米提[2] 陈凤辉[1] 许国军[1] 庞海玉[3] 邱长春[3] 

机构地区：[1]新疆医科大学第一附属医院,乌鲁木齐830054 [2]新疆维吾尔自治区人民医院,乌鲁木齐830049 [3]中国医学科学院基础医学研究所,北京100005

出　　处：《北京大学学报（医学版）》2011年第4期591-595,共5页Journal of Peking University:Health Sciences

基　　金：美国中华医学基金(CMB:96-657);“十一五”国家科技支撑计划重点项目(2006BAI19B07);国家重点基础研究发展计划(973计划,2006CB504103);医学分子生物学国家重点实验室特别基金(2060204)资助~~

摘　　要：目的:探讨"罗布人后裔"的生理特征。方法:用方便取样方法,从新疆维吾尔自治区尉犁县居住的罗布人后裔中抽取594人,通过现场问卷调查、体格检查和生化测定获取研究对象的人口学特征、生理及生化指标值。结果:"罗布人后裔"血压异常率男性为47.1%,女性为45.4%,男女间差异无统计学意义。女性体重指数≥28 kg/m2的比例高于男性,分别为41.2%vs.32.7%,男女间差异具有统计学意义(P<0.05)。男性三酰甘油和高密度脂蛋白的异常比例均高于女性,分别为36.6%vs.25.5%(P=0.003 7),9.7%vs.3.9%(P=0.003 8)。多因素分析结果显示,BMI和三酰甘油的升高是罗布人后裔发生血压异常的危险因素。结论:初步结果表明,"罗布人后裔"的主要生理特征是高血脂、多肥胖和血压水平异常率高,而高血脂和肥胖可能是该人群高血压多发的主要危险因素。Objective： To investigate the physiological characteristics in ＂offspring of Lop Nor people＂,a special population from the Lop Nor dried up in Xinjiang.Methods： A total of 594 subjects were selected by convenience sampling method from Yuli County,Xinjiang Uygur Autonomous Region.All data were obtained from each person by the questionnaire and standard physical examinations.Results： The prevalence of hypertension for ＂offspring of Lop Nor people＂ was 47.1% for males and 45.4% for females,respectively.The prevalence of high body mass index（BMI≥28 kg/m2） was higher in females than that in males,with 41.2% vs.32.7%.The prevalence of abnormal TG in males was higher than that in females,36.6% vs.25.5%（P=0.003 7）.And prevalence of abnormal HDL in males was hig-her than that in females,9.7% vs.3.9%（P=0.003 8）.The results of multivariate analysis revealed that BMI and TG were the risk factors for hypertension in ＂offspring of Lop Nor people＂.Conclusion： The preliminary results show that the main physiological characteristics are high blood lipid,high prevalence of hypertension and obesity in ＂offspring of Lop Nor people＂.High blood lipid and obesity might be the main risk factors for hypertension in this population.

关 键 词：罗布人后裔 高血压 血脂异常 肥胖 

分 类 号：R339.59[医药卫生—人体生理学]