新疆维吾尔自治区汉、维吾尔和哈萨克族人群颈动脉内中膜厚度的流行病学调查  

Epidemiological survey of carotid artery intima-media thickness in Han, Uygur and Hazakh population of Xinjiang Uygur autonomous region

作　　者：杨毅宁[1] 赵文丽[1] 马依彤[1] 谢翔[1] 刘芬[1] 黄定[1] 李晓梅[1] 黄莺[1] 陈邦党[1] 马翔[1] 付真彦[1] 古丽娜尔·白托拉[1] 于子翔[1] 

机构地区：[1]新疆医科大学第一附属医院心脏中心,乌鲁木齐830054

出　　处：《中华心血管病杂志》2011年第8期755-758,共4页Chinese Journal of Cardiology

基　　金：新疆维吾尔自治区重大科技专项课题（200733146-3）

摘　　要：目的了解新疆维吾尔自治区汉、维吾尔和哈萨克族35岁及以上人群颈动脉内中膜厚度（intima—media thickness，IMT）及其相关危险因素。方法采用整群随机抽样方法抽取新疆维吾尔自治区汉、维吾尔和哈萨克族35岁及以上居民进行颈动脉IMT及其相关危险因素的横断面调查。结果新疆维吾尔自治区35岁及以上人群的颈动脉IMT汉族为（0．0761±0．0283）cm，维吾尔族为（0．0663±0．0262）cm，哈萨克族为（0．0781±0．0274）cm，不同民族之间的IMT差异均有统计学意义（均P〈0．05）。汉族颈动脉IMT男性为（0．0807±0．0288）cm，女性为（0．0717±0．0270）（3111（P〈0．01）；维吾尔族颈动脉IMT男性为（0．0706±0．0270）cm，女性为（0．0633±0．0252）cm（P〈0．01）；哈萨克族颈动脉IMT男性为（0．0794±0．0280）cm，女性为（0．0768±0．0268）cm（P〈0．01）。简单线性相关分析显示，新疆维吾尔自治区汉、维吾尔和哈萨克族人群年龄、收缩压、舒张压、空腹血糖、总胆固醇、踝臂指数与颈动脉IMT相关（r值分别为0．176，0．168，0．167，0．053，0．097和0．067，均P〈0．05）。结论新疆维吾尔自治区哈萨克族的颈动脉IMT大于汉族和维吾尔族。IMT与年龄、收缩压、舒张压、空腹血糖、总胆固醇、踝臂指数相关。Objective To investigate carotid artery intima-media thickness （IMT） and the correlated risk factors in Han, Uygur, Hazakh residents over 35 years old of Xinjiang Uygur autonomous region. Method Cross-sectional and cluster sampling random selected method was carried out for residents over 35 years old in Han, Uygur, Hazakh population of Xinjiang to investigate IMT and correlated risk factors. Results IMT of Han, Uygur, Hazakh residents over 35 years old of Xinjiang Uygur autonomous region was （0. 0761 ± 0. 0283 ） era, （0. 0663 ± 0. 0262） cm, and （0. 0781± 0. 0274） cm, respectively. There were significantly difference between various nationality（ all P 〈 0. 05 ）. IMT was thicker in male Han people than in female Han people[ （0. 0807 ±0. 0288） cm vs. （0. 0717 ±0. 0270） cm, P 〈0. 01 ]and in male Uygnr than in female Uygur residents [ （0. 0706 ±0. 0270）cm vs. （0. 0633 ±0. 0252） cm, P 〈0. 01 ]and in male Hazakh and female Hazakh residents [ （0. 0794 ± 0. 0280） cm vs. （0. 0768± 0. 0268） era, P 〈 0. 01 ]. Linear correlation analysis showed that age（ r = 0. 176, P 〈 0. 05 ）, systolic blood pressure （r = 0. 168, P 〈 0. 05 ）, diastolic blood pressure （ r = 0. 167, P 〈 0. 05 ）, fasting blood glucose （ r = 0. 053, P 〈 0. 05 ）, total cholesterol（r = 0. 097, P 〈 0. 05 ） and ankle brachial index （ r = 0. 067, P 〈 0. 05 ） were significantly correlated with IMT. Conclusions Our results showed that IMT was thicker in Hazakh residents than in Han and Uygur residents. IMT was closely related to known cardiovascular risk factors including age,systolic blood pressure, diastolic blood pressure ,fasting blood glucose, total cholesterol and ankle brachial index level.

关 键 词：动脉硬化 颈动脉 人种群 

分 类 号：R543.5[医药卫生—心血管疾病]