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作 者:马玉林[1] 孙静[1] 桑韩飞[1] 王雷[2] 肖昭扬[1] 熊利泽[1]
机构地区:[1]第四军医大学西京医院麻醉科,陕西西安710032 [2]第四军医大学航空航天医学系航空航天生物动力学教研室,陕西西安710032
出 处:《现代生物医学进展》2011年第17期3245-3247,共3页Progress in Modern Biomedicine
基 金:全军"十一五"科研课题(专项)(08Z032)
摘 要:目的:研制一种在正加速度作用下能实时观测大鼠行为状态的实验视频采集装置,为研究正加速度导致脑损伤的病理生理机制和防治措施提供新的方法。方法:依据正加速度对大鼠体位的要求和离心机特殊的环境,通过特制的大鼠座舱和无线视频采集单元来实现对动物离心机中正加速度作用下大鼠行为状态的实时观测;固定大鼠的座舱主要由胸部固定圈、身长调节圈、头部运动限制框构成;无线视频采集单元由2.4 G无线摄像头、无线信号接收器、信号放大器、计算机以及视频采集软件组成。结果:座舱特殊的大鼠固定方式,既满足了正加速度对体位的要求,又不影响对大鼠行为状态的观测,2.4 G无线视频采集技术保证视频信号在离心机高速旋转环境下的实时传输和观测,视频画面清晰流畅,并且能保存视频供回放分析。结论:动物离心机无线视频采集装置可用于正加速度作用下大鼠行为状态的实时观测与研究。Objective: To develop a kind of experimental video recording device to instantly observe rats behavior under positive acceleration, provide the new methods to study the pathophysiological mechanisms of brain injury induced by positive acceleration as well as for prevention and treatment brain injury. Methods: According to the requirement for rats body status under positive acceleration and special environment of centrifuge machine, through specialized-made rats cabin and placement of wireless video recording device to realize the instantly monitor of rats behavior under positive acceleration. Fixed rats cabin is made of chest fastening circle, body length modulator and head fixed frame; while wireless video recording device is composed by 24G wireless video recorder, wireless signal receiver, signal amplifier, computer and software for video signal collection. Results: The specialized fixed methods of rats cabin not only satisfy the demand for body status under positive acceleration, but also not affect the observation of rats behavior. 24G wireless video recording device guarantee transmission of video signal, provide the high quality-video pictures and video replaying for future analysis. Conclusion: Wireless video recording device implemented on the high velocity animal centrifuge could instantly obverse and study the rats behavior under positive acceleration.
关 键 词:动物离心机 正加速度 大鼠座舱 大鼠行为状态 无线视频采集
分 类 号:Q95-3[生物学—动物学] R852.21[医药卫生—航空、航天与航海医学]
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