关于HCMV潜伏感染与激活感染研究的新进展  

Research of Latent Infection and Active Infection of Human Cytomegalovirus

作　　者：单幼兰[1] 张笋华 陈伟华 江培学 陈家梁 

机构地区：[1]重庆医科大学附属第二医院感染科实验室,重庆400010 [2]常州千红生化制药有限公司,江苏常州213001 [3]复星医学科技发展有限公司,上海200233

出　　处：《现代生物医学进展》2011年第17期3382-3385,共4页Progress in Modern Biomedicine

摘　　要：人巨细胞病毒(HCMV)是疱疹病毒科中最大的病毒,结构复杂,其感染在人群中非常普遍,近年来免疫妥协(immunocompromised)群体尤其是移植群体中的HCMV潜伏感染和激活感染越来越受到临床重视。本文就HCMV的感染与免疫、HCMV的致病机制、宿主的抗感染与免疫、HCMV的免疫逃逸、HCMV的潜伏与激活及HCMV相关研究的困境与展望近年来此方面研究新进展作一简要综述。Human Cytomegalovirus is the biggest virus of Herpesviridae,with complex Structure,it＇s infection is very common in the crowd.Reeently,HCMV latent infection and active infection in immunocompromised group （especially in the transplanting group） brought to the forefront in clinical.The purpose of this report is to present the infection and immunity of HCMV,the pathogenic mechanism of HCMV,the anti-infection and immunity of Host,the immunologic escape of HCMV,the latent infection and active infection of HCMV and The progress of the research in this field.

关 键 词：人巨细胞病毒 潜伏感染 激活感染 免疫逃逸 

分 类 号：R373[医药卫生—病原生物学]