综合疗法对神经根型颈椎病患者血浆SP的影响及其疗效观察  

Therapeutic Effectiveness of Comprehensive Therapy for Patients with Cervical Spondylotic Radiculopathy and Its Influence on the Level of Plasma Substance P

作　　者：唐雷[1] 张红星[2] 黄国付[2] 周利[2] 邹燃[2] 安雪[1] 祁青[1] 

机构地区：[1]湖北中医药大学,武汉430065 [2]武汉市中西医结合医院针灸科,武汉430022

出　　处：《中国康复》2011年第1期33-35,共3页Chinese Journal of Rehabilitation

基　　金：2006年武汉市科技攻关计划(No.20065009138-05)

摘　　要：目的:观察综合疗法对神经根型颈椎病患者血浆P物质(SP)的影响及其临床疗效。方法:80例神经根型颈椎病患者随机分为综合组20例,给予针刺、推拿及药物治疗;对照1、2、3组各20例,分别采用针刺结合推拿、针刺结合药物及推拿结合药物治疗,治疗前后分别测定各组患者血浆SP浓度并观察临床疗效。结果:治疗12 d后,各组患者血浆SP浓度均明显降低,综合组明显低于对照各组(均P<0.01)。临床疗效比较,综合组痊愈显效率明显高于对照1、2、3组(95.0%与60.0%、63.2%、60.0%,P<0.05)。结论:多种疗法综合治疗神经根型颈椎病可显著降低血浆SP的浓度,减轻疼痛,促进临床疗效的提高。Objective：To observe clinical efficacy of comprehensive therapy for patients with cervical spondylotic radiculopathy and its influence on the level of plasma substance P（SP）.Methods：Eighty cases of cervical spondylotic radiculopathy were randomly divided into treatment group（acupuncture,massage with drug）,control group 1（acupuncture combined with massage）,control group 2（acupuncture combined with drug）,control group 3（massage combined with drug）,every 20 cases in each group.The clinical efficacy was observed,and plasma SP was measured before and after treatment.Results：After treatment for 12 days,plasma SP levels were significantly reduced in all groups,and those in treatment group were significantly lower than in control groups（all P0.01）.The effective rate in treatment group（95.0%） was significantly higher than in control groups 1,2 and 3（60.0%,63.2% and 60.0% respectively,P0.05）.Conclusion：The comprehensive therapy for cervical spondylotic radiculopathy can significantly reduce the plasma SP level,relieve the pain and improve the therapeutic efficacy.

关 键 词：神经根型颈椎病 综合疗法 SP 

分 类 号：R681.55[医药卫生—骨科学]