超微电极快速扫描法检测六味地黄丸中的丹皮酚  

Determination of Paeonol in Liuwei Dihuang Pill by Quick Scan on the Ultramicroelectrode

作　　者：张叶[1] 吴剑[1] 李端[1] 赵波[1] 

机构地区：[1]安徽中医药高等专科学校,安徽芜湖241000

出　　处：《辽宁化工》2011年第8期884-886,共3页Liaoning Chemical Industry

基　　金：安徽中医药高专校级基金ZRKX1014

摘　　要：目的利用丹皮酚在超微电极上的电化学行为,建立六味地黄丸中丹皮酚含量监控方法。方法以50%的乙腈-水为提取液,超声提取六味地黄丸中的丹皮酚,使用超微电极、快速方波伏安扫描（SWV）技术进行电化学检测。结果可获得丹皮酚的重现性良好的氧化峰,该峰电流与丹皮酚的浓度在1×10-3~5×10-7 mol/L范围内成呈良好的线性关系,线性回归方程为：I=4 012.12C＋0.002（r=0.999 3）,检出限为1×10-7mol/L。结论该方法快速、准确、检测灵敏度高、重现性好、仪器便携,在六味地黄丸质量监控方面有广泛的应用前景。A new fleetness and accurate method to measure paeonol had been established by the electrochemical behaviours of paeonol on ultramicroelectrode.The ultramicroelectrode and SWV technique were used to determine paeonol in the NaOH-NaH2PO4 buffer solution（pH=11.21）.A sensitive oxidization peak of paeonol was obtained in this buffer solution.The peak current was directly proportional to concentration of paeonol in the range of 1.0×10-3～5.0×10-7 mol/L with the detection limit of 1×10-7 mol/L.The new method is accurate and dependable,operating simple,fleetness,easily reappear,and it has been applied to determine paeonol in Liuwei Dihuang Pill with satisfactory results.

关 键 词：六味地黄丸 丹皮酚 超微电极 

分 类 号：O657[理学—分析化学]