2009年综合医院细菌耐药性监测分析  

Results of monitoring of bacterial drug resistance in an integrated hospital in 2009

作　　者：符健[1] 蔡笃运[1] 贾杰[1] 

机构地区：[1]海南省人民医院感染科,海南海口570311

出　　处：《中国热带医学》2011年第8期973-975,共3页China Tropical Medicine

摘　　要：目的了解2009年某综合医院医院感染病原菌的分布特点及其对常用抗菌药物的耐药状况,为医院感染的预防与控制提供参考。方法对某综合医院2009年1~12月分离的病原菌作回顾性分析。结果共分离医院感染病原菌1 885株,其中革兰氏阴性杆菌1 282株,占68.0%,主要是：铜绿假单胞菌、大肠埃希菌、肺炎克雷伯菌。肠杆菌科对碳青霉烯类抗菌素耐药率均在28%以下。铜绿假单胞菌对氨苄西林/舒巴坦、左氧氟沙星、美洛培南的耐药率分别为18.5%3、6.4%、41%。革兰氏阳性球菌414株,占21.9%,主要以葡萄球菌为主,其中耐甲氧西林金黄色葡萄球菌（MRSA）为63株,检出率为35.79%。结论本次分离的肠杆菌属对头孢菌类抗菌素耐药率高,应严格控制头孢菌素类抗菌素的临床应用。Objective To survey the pathogens distribution and their drug-resistance characteristics of the bacteria in an integrated hospital in 2009.Methods The pathogens isolated from clinical specimens in 2009 were analyzed.Results A total of 1 885 nosocomial pathogens were collected in 2009.Gram-negative bacilli accounted for 68%（1 282 stains）.The main pathogens were Pseudomonas aeruginosa,Escherichia coli,Kledsiella pneumoniae.The resistance of Enterobacteriaceae to carbapenems antibiotics was less than 28%.While the resistance of Pseudomonas aeruginosa to carbapenems/subacta,levofloxacin and peropenem were 18.5%,36.4%,41.0% respectively.Gram-posistive cocci accounted for 21.9%（414 stains）.The main pathogen was Staphylococci in which methicillin-resistant S.aureus（MRSA） were 63 stains（35.79%）.Conclusion The resistance rates of enterobacter to cephalosporins was hight and the use of cephalosporins be trictly controlled.

关 键 词：细菌 耐药监测 药敏 

分 类 号：R515[医药卫生—内科学]