Eco-friendly and Efficient Synthesis of 2,3-Dihydroquinazolin-4（1 H）-ones  

作　　者：Majid, Ghashang Kobra, Azizi Hamed, Moulavi-Pordanjani Hamid Reza, Shaterian 

机构地区：[1]Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, PO Box 98135-674, Zahedan, Iran

出　　处：《Chinese Journal of Chemistry》2011年第8期1617-1623,共7页中国化学（英文版）

摘　　要：A simple and facile method for the synthesis of 2,3-dihydroquinazolin-4（1H）-ones through the direct cyclocon- densation of one-pot three-component cyclocondensation of isatoic anhydride, ammonium acetate （or primary amines） and aldehydes; and anthranilamide and aldehydes using silica supported ferric chloride （SiO2-FeCl3） as catalyst under solvent-free conditions is described.A simple and facile method for the synthesis of 2,3-dihydroquinazolin-4（1H）-ones through the direct cyclocon- densation of one-pot three-component cyclocondensation of isatoic anhydride, ammonium acetate （or primary amines） and aldehydes; and anthranilamide and aldehydes using silica supported ferric chloride （SiO2-FeCl3） as catalyst under solvent-free conditions is described.

关 键 词：SOLVENT-FREE synthetic methods aldehydes 2 3-dihydroquinazolin-4（1H）-one ANTHRANILAMIDE isatoicanhydride 

分 类 号：TQ252.4[化学工程—有机化工] X793[环境科学与工程—环境工程]