A Carbon Material as a Strong Protonic Acid for Efficient Synthesis of 4(3H)-Quinazolinones  被引量:5

A Carbon Material as a Strong Protonic Acid for Efficient Synthesis of 4(3H)-Quinazolinones

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作  者:Tavakoli-Hoseini, Niloofart Davoodnia, Abolghasem 

机构地区:[1]Department of Chemistry, Mashhad Branch, Islamic Azad University, Mashhad, Iran

出  处:《Chinese Journal of Chemistry》2011年第8期1685-1688,共4页中国化学(英文版)

摘  要:Carbon-based solid acid catalyst has been applied to catalyzing the synthesis of 4(3H)-quinazolinones from the cyclization reaction of 2-aminobenzamide with aroyl chlorides. The results showed that the catalyst was very efficient with the average yield over 85%. This carbon material with strong protonic acid sites as heterogeneous cata- lyst has some advantages such as high activity, strikingly simple work-up procedure, non-pollution, and reusability, which will contribute to the green process greatly.Carbon-based solid acid catalyst has been applied to catalyzing the synthesis of 4(3H)-quinazolinones from the cyclization reaction of 2-aminobenzamide with aroyl chlorides. The results showed that the catalyst was very efficient with the average yield over 85%. This carbon material with strong protonic acid sites as heterogeneous cata- lyst has some advantages such as high activity, strikingly simple work-up procedure, non-pollution, and reusability, which will contribute to the green process greatly.

关 键 词:carbon-based solid acid heterogeneous catalysis 2-aminobenzamide aroyl chlorides CYCLIZATION 

分 类 号:TQ127.11[化学工程—无机化工] O633.21[理学—高分子化学]

 

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