无症状乙肝病毒携带状态对妊娠期糖尿病及妊娠结局的影响  

Effect of asymptomatic hepatovirus B carrier on gestational diabetes mellitus and outcome of pregnancy

作　　者：吴小妹[1] 凌奕[1] 李跃萍[1] 金松[1] 

机构地区：[1]海南医学院附属医院妇产科,海南海口570102

出　　处：《海南医学院学报》2011年第9期1244-1246,共3页Journal of Hainan Medical University

基　　金：海南医学院科研基金资助学报项目(0020110330)~~

摘　　要：目的:探讨无症状乙肝病毒(HBV)携带状态对妊娠期糖尿病(GDM)的发生率及对妊娠结局的影响。方法:对1 243例孕妇的HBV血清学、肝功能、血糖进行检测,并记录妊娠结局。比较无症状HBV阳性与HBV阴性孕妇GDM的发生率及妊娠结局。结果:1 243例孕妇中HBV感染率约为10%,HBV感染的孕妇中GDM的发生率为22.7%,无HBV感染的孕妇中GDM的发生率为12.7%,两者比较差异有统计学意义(P<0.05)。HBV感染的GDM的妊娠结局与无HBV感染的GDM的妊娠结局差异无统计学意义(P>0.05)。结论:HBV表面抗原阳性较HBV表面抗原阴性孕妇GDM的发生率增高,有统计学差异,但并不改变其妊娠结局。Objective： To investigate the effect of hepatitis B virus（HBV） carriers on gestational diabetes mellitus（GDM） and outcome of pregnancy.Methods： A total of 1 243cases of gravidas were detected,including hepatitis B virus serology,liver function and glucose.The outcome of pregnancy and incidence of GDM were observed and compared between HBsAg（＋） and HBsAg（-）.Results： The infection rate of patients with HBV was 10%.The incidence of GDM was 22.7% percent with HBV patients and 12.7% in patients without HBV.There was significant difference in the incidence（P0.05）,but no difference in the outcome of pregnancy（P0.05）.Conclusions： The incidence of GDM is higher in patients with HBV positive.But it has no effect on the outcome of pregnancy.

关 键 词：乙肝病毒 妊娠期糖尿病 妊娠结局 

分 类 号：R714[医药卫生—妇产科学]