左氧氟沙星联合黄芪注射液治疗难治性肺结核疗效分析  

Clinical observation of astragalus jection combined with Levofloxacin on refractory pulmonary tuberculosis

作　　者：吕小会 苟超伦 

机构地区：[1]西安市结核病胸部肿瘤医院,陕西西安710061

出　　处：《海南医学院学报》2011年第10期1350-1352,共3页Journal of Hainan Medical University

基　　金：海南医学院科研基金资助学报项目(0020110366)~~

摘　　要：目的:探讨左氧氟沙星联合黄芪注射液治疗难治性肺结核的临床疗效。方法:83例难治性肺结核患者随机分成观察组(49例)和对照组(34例),对照组患者应用常规2HRZSE/6HRE化疗,观察组患者在此基础上加用左氧氟沙星和黄芪注射液,两组患者疗程为8个月,比较两组痰菌阴转率、X线检查情况、空洞闭合情况及不良反应发生率。结果:治疗8个月后,观察组痰菌阴转率、X线检查显效率、空洞愈合率均明显高于对照组,不良反应发生率明显低于对照组,差异有统计学意义(P均<0.05)。结论:左氧氟沙星联合黄芪注射液能明显改善难治性肺结核患者的临床症状,临床效果显著,值得推广。Objective： To explore the clinical efficacy of astragalus jection combined with Levofloxacin on refractory pulmonary tuberculosis.Methods： 83cases with refractory pulmonary tuberculosis were randomly divided into observation group and control group.The chemotherapy regimen of 2HRZSE/6HRE was used to control group.astragalus jection combined with Levofloxacin was given to observation group on the base of control group,the course was eight months in two groups.Results：The bacterial negative rate,th eefficacy rate of X-ray,cavity healing rate and The adverse reactions rate in observation group compared with those in control goup there all were statistical difference（P0.05）.Conclusions： Astragalus jection combined with Levofloxacin can improve the symptoms of the patients with refractory pulmonary tuberculosis and the clinical efficacy is significant.

关 键 词：难治性肺结核 左氧氟沙星 黄芪注射液 

分 类 号：R521[医药卫生—内科学]