宫颈液基细胞学检查在宫颈病变筛查中的临床应用  

The clinical application of liquid based cytologic test on cervical carcinoma screening

作　　者：董健余 

机构地区：[1]浙江省玉环县中医院病理科,317600

出　　处：《中国基层医药》2011年第17期2350-2352,共3页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的探讨宫颈液基细胞学检查（TCT）技术在预防与筛查宫颈病变中的临床应用价值。方法9582例患者进行TCT检测，对阳性病例再进行阴道镜检查加组织活检。结果9582例标本中，异常涂片有392例，其中ASC311例（3．24％），LSIL45例（0．47％），HSIL13例（0．13％），AGC21例（0．22％），SCC1例（0．01％）。在所有阳性病例中，35—39岁组人群的阳性检出率最高（20．92％），30—34岁组其次（20．66％）。TCT与组织活检检查的总体符合率为58．67％，ASC、LSIL、HSIL、AGC、SCC的符合率分别为54．98％、80．00％、100．00％、42．86％、100．00％。TCT对HSIL及以上的病变的阳性符合率明显高于LSIL及以下的病变，差异有统计学意义（t：9．810，P=0．002）。结论TCT结合阴道镜下病理检查是筛查并及早发现宫颈癌的癌前病变的有效方法。Objective To study the clinical application value of TCT technology in prevention and screening cervical lesions. Methods 9 582 cases received TCT detection. The positive patients received further biopsy vaginal endoscopy. Results In 9 582 specimens, there were 392 abnormal smear including 311 ASC （ 3.24% ） , 45 LSIL （0. 47% ） ,13 HSIL（0. 13% ） ,21 AGC（0. 22% ） ,1 SCC（0. 01% ）. The 35 -39 age group had the highest positive rate（20. 92% ） and the 30 -35 age group was prior（20. 66% ） in the positive group. The coordination rate between TCT and biopsy endoscopy was 58. 67%. The coordination rates for ASC, LSIL, HSIL, AGC, SCC were 54. 98% , 80. 00% ,100. 00% ,42. 86%, 100. 00% respectively. The effect of TCT on the positive coordination rate of upper HSIL was higher than lower HSIL（ X^2=9. 810,P =0. 002）. Conclusion The combination of TCT and biospy endoscope was an effective method to screen the early cervical cancer.

关 键 词：宫颈液基细胞 宫颈疾病 

分 类 号：R711[医药卫生—妇产科学]