深圳市社区人群甲状腺功能紊乱情况调查  

Investigation of the Thyroid Dysfunction Prevalence in Community Population in Shenzhen

作　　者：吴正林[1] 黄英[2] 范菲楠 钟小强[1] 吴意 陆学东[1] 

机构地区：[1]深圳市第四人民医院检验医学部,广东深圳518033 [2]深圳市第四人民医院血液透析室,广东深圳518033

出　　处：《现代检验医学杂志》2011年第4期138-139,143,共3页Journal of Modern Laboratory Medicine

摘　　要：目的调查深圳地区人群甲状腺功能紊乱的患病率及其特点。方法随机抽取876份在2010年1月～7月期间参加深圳市第四人民医院健康体检的成年人血清标本。先检测血清中促甲状腺激素（TSH）结果异常者，再检测游离甲状腺激素T3（FT3）和游离甲状腺激素T4（FT4）。结果在876例健康体检者中甲状腺功能异常的患病率为4．11％，甲状腺功能亢进（甲亢）患病率为0．34％，亚临床甲亢患病率为0．68％，甲状腺功能减退（甲减）的患病率为0．68％，亚临床甲减患病率为2．40％。女性患病率高于男性，差异有统计学意义（x^2=5．56，P〈0．01），亚临床甲状腺功能紊乱的患病率（3．08％）显著高于临床甲状腺功能紊乱的患病率（1．02％）。结论亚临床甲状腺功能异常是深圳地区人群甲状腺功能紊乱的常见类型，且亚临床型甲战患病率高于亚临床型甲亢。Objective To investigate the prevalence and the characteristic of thyroid dysfunction in community population of Shenzhen. Methods Serum samples of 876 adults who participate in healthy physical examination in Shenzhen Fourth Peo pie＇s Hospital were randomly selected in January 2010 ~ July 2010 period. Serum bloods were assayed for thyrotropin （TSH） ,then FT3 and FT4 were detected in those of abnormal thyrotropin. Results The prevalence of thyroid dysfunction in 876 healthy physical examination adults was 4. 11%. Prevalences of overt hyperthyroidism,subclinical hyperthyroidism, overt hypothyroidism and subclinical hypothyroidism were 0. 34% ,0. 68% ,0. 68% and 2- 40% respectively. Female prevalence was higher than men, the difference was statistically significant （x^2 = 5.56,P〈 0. 01）, the prevalence of subclinical thyroid dysfunction （3.08%） was significantly highly than the clinical thyroid dysfunction （1.02%）. Conclusion Subclin- ical thyroid dysfunction is a common type of thyroid dysfunction in community population of Shenzhen,and the prevalence of subclinical hypothyroidism is higher than subclinical hyperthyroidism.

关 键 词：甲状腺 甲状腺功能 亚临床型 

分 类 号：R581[医药卫生—内分泌] R392.11[医药卫生—内科学]