溶析结晶法分离莱鲍迪甙A的工艺研究  

Study on the separation of rebaudioside A by solventing-out crystallization

作　　者：赵昊 彭奇均 

机构地区：[1]江南大学化学与材料工程学院,江苏无锡214122

出　　处：《应用化工》2011年第8期1310-1313,共4页Applied Chemical Industry

基　　金：国家十一五科技支撑计划项目(2006BAD05A07)

摘　　要：采用溶析结晶法分离甜菊糖苷中的莱鲍迪甙A(RA),考察溶析剂及其含量、溶液浓度、结晶温度、结晶时间对结晶率和分离系数〔0.87×SRA/(Stotal-SRA)〕的影响。结果表明,在乙酸乙酯含量50%,溶液浓度20 g/L,结晶温度18℃,结晶时间8 h的条件下,结晶率为0.34,分离系数为3.8。Rebaudioside A was separated from steviol glycosides by solventing-out crystallization. The effects of solventing-out agent and its content, concentration of steviol glycosides, crystallization tempera ture and crystallization time on crystallization rate and separation coefficient （0.87 × SRA/（ StotaI -SRA）in the crystal product were discussed. The results showed that the percent crystallization rate was 0.34 and separation coefficient was 3.8, under the optimized conditions, which were as follows ： content of ethyl acetate 50%, concentration of steviol glycosides 20 g/L, 8h. crystallization temperature 18 ℃ ,crystallization time 8h.

关 键 词：莱鲍迪甙A 溶析结晶 分离 

分 类 号：TQ028.9[化学工程] TS210.1[轻工技术与工程—粮食、油脂及植物蛋白工程]