神经外科病原菌类型及耐药性变化分析  

Analysis of the types of pathogenic bacteria found in the neurosurgery department and changes in drug resistance

作　　者：李芳芹[1] 屈玲[1] 

机构地区：[1]延安大学附属医院检验科微生物室,陕西延安716000

出　　处：《中国病原生物学杂志》2011年第8期611-613,共3页Journal of Pathogen Biology

摘　　要：目的了解2007~2010年神经外科感染的病原菌类型及耐药性。方法对神经外科分离的主要病原菌类型及耐药性变化进行回顾性分析。结果 G-杆菌2007~2008年的分离率为69.23%,2009~2010年下降至47.89%,G＋球菌的分离率从23.60%上升至27.60%,念珠菌的分离率从5.59%上升至11.83%。大肠埃希菌产ESBLs由50.00%上升到61.54%,肺炎克雷伯产ESBLs由36.36%上升到56.52%,MRSA由20.00%上升到45.45%。结论神经外科感染的病原菌以耐药菌株为主,对常用抗生素严重耐药和多重耐药,对高效抗生素的耐药率在不断上升。应加强抗生素的使用管理,控制院内感染,延缓耐药菌株产生。Objective To ascertain the types of pathogens in neurosurgery and their drug resistance from 2007-2010.Methods The main types of pathogenic bacteria isolated in neurosurgery and changes in drug resistance were studied retrospectively.Results G-bacilli were isolated at a rate of 69.23% from 2007-2008,and this rate declined to 47.89% from 2009-2010.G＋ cocci were isolated at a rate of 23.60%,and this rate rose to 27.60%.Candida spp.were isolated at a rate of 5.59%,and this rate rose to 11.83%.ESBL-producing E.coli was isolated at a rate of 50.00%,and this rate rose to 62.00%.ESBL-producing K.pneumonia was isolated at a rate of 36.00%,and this rate rose to 56.00%.MRSA was isolated at a rate of 20.00%,and this rate rose to 45.45%.Conclusion The pathogenic bacteria in neurosurgery were primarily drug-resistant strains.These strains were highly resistant to a number of common antibiotics.The rate of resistance to potent antibiotics is increasing.Rational use of antibiotics should be enhanced and nosocomial infections should be controlled.These steps should delay the development of drug-resistant strains.

关 键 词：神经外科 病原菌 耐药性 

分 类 号：R378[医药卫生—病原生物学]