102例注射用阿奇霉素不良反应/事件报告分析  

Analysis of 102 Cases of ADR/ADE Caused by Azithromycin for Injection

作　　者：程毅 刘仕杰[2] 徐作国 

机构地区：[1]莱阳市中医医院,山东莱阳265200 [2]烟台市莱阳中心医院,山东莱阳265200 [3]烟台市心理康复医院,山东莱阳265200

出　　处：《中国药物警戒》2011年第9期557-559,共3页Chinese Journal of Pharmacovigilance

摘　　要：目的探讨阿奇霉素不良反应/事件的发生情况,为临床安全用药提供参考。方法对两所二、三级综合性医院2007～2010年间药品不良反应/事件报告进行统计分析。结果阿奇霉素不良反应/事件累及5大系统-器官,涉及15个病种,以消化系统不良反应和过敏反应较多。53.92%不良反应为婴幼儿及儿童患者,74.51%不良反应发生在用药2小时内。结论阿奇霉素不良反应/事件消化系统和过敏反应较多,婴幼儿应慎用。Objective To investigate Azithromycin adverse reaction/event（ADR/ADE）occurrence which could provide reference for clinical drug safety.Methods Statistical analysis of the ADR/ADE testing data of two general hospitals for 4 years from 2007 to 2010.Results Azithromycin ADR/ADE involving 15 types of disease in the five organ system.More adverse reactions were allergic reactions and digestive system reactions,53.92% for infants and children,74.51% occurred within 2 hours.Conclusion More Azithromycin adverse reactions/event in digestive system and allergic reactions,used with caution in infants and young children.

关 键 词：阿奇霉素 不良反应/事件 消化系统 过敏 

分 类 号：R978.1[医药卫生—药品] R994.11[医药卫生—药学]