银川市2008-2009年手足口病流行特征及病原学监测分析  

Epidemic Features and Etiology of HFMD in Yinchuan in Year 2008/2009

作　　者：雷静[1] 范晓宇[2] 胡皓[1] 张嫣平[1] 李萍[1] 杨嵘[1] 

机构地区：[1]银川市疾病预防控制中心,银川750001 [2]银川市第一人民医院,银川750001

出　　处：《宁夏医科大学学报》2011年第8期742-745,F0002,共5页Journal of Ningxia Medical University

摘　　要：目的了解银川市手足口病发病情况、病原学、临床等流行病学规律及发生发展趋势。方法应用流行病学监测研究方法(Prevalence study)对银川市手足口病流行特征、实验室病原学检测、爆发疫情等进行监测分析研究,应用现场流行病学对临床资料进行追踪调查和研究分析。结果 2008年7月1日-2009年6月30日银川市共报告1774例手足口病,报告发病率为113.88/10万;6个县区均有病例报告,以城市为主的三区发病显著高于以农村为主的三县;主要集中在7岁以下儿童;以散居儿童和幼托儿童为主;6月份达到最高峰;共发生22起手足口病暴发疫情,均发生在幼托机构,其中民办幼儿园发生17起;5起构成一般突发公共卫生事件;共采集134例手足口病患者的176份标本进行病毒分离,其中EV71病毒22例(40.74%)、Cox-A16病毒18例(33.33%)、其它肠道病毒14例(25.93%);阳性检出率30.68%。临床表现主要为发热,部分伴有手、足、口腔、肛周等部位皮疹或疱疹,大多出现咽痛、咳嗽,个别有呕吐等,少数出现神经系统症状。结论加强手足口病病例及实验室监测,提高诊治水平,加大宣传力度,重点加强城市三区、托幼机构尤其是民办幼儿园的疫情防控,建立有效的手足口病综合防控机制。Objective To explore the epidemic features and etiology of HFMD in Yinchuan in year 2008/2009.Methods The epidemiology monitor research technique were used to monitor the epidemic features of HFMD in Yinchuan.The laboratory examination were used to monitor etiology of HFMD.Results From July 1st,2008-June 30,1774 cases with Hand-foot-mouth disease were reported and the report incidence rate was 113.88/100,000;Cases distributed all the 6 county areas;The report incidence rate in urban areas was significantly higher than that in rural areas;cases Mainly concentrated in children below 7 years old;In June the case reports reached the high point;20 outbreaks of HFMD were observed and they occurred in the kindergartens;EV71 virus were isolated in 22 examples（40.74%）,CoxA16 virus in 18 examples（33.33%）,other enteric virus in 14 examples（25.93%）.Conclusion Monitoring and report of the foot and mouth disease should be emphasized and strengthened for improving the level of prevention and treatment.

关 键 词：手足口病 流行特征 病原学 监测分析 

分 类 号：R725.1[医药卫生—儿科] R181.3[医药卫生—临床医学]