围绝经期综合征肝郁病理与雌性激素的相关性研究  

Interrelationship study of liver depression and estrogen in perimenopausal syndrome

作　　者：梁文娜[1] 李灿东[1] 甘慧娟[1] 高碧珍[2] 杨敏[1] 王洋[1] 李红[3] 

机构地区：[1]福建中医药大学中医证研究基地,福州350108 [2]福建中医药大学中西医结合学院,福州350108 [3]福建省立医院中医科,福州350007

出　　处：《中华中医药杂志》2011年第9期1961-1963,共3页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家自然科学基金(No.30772697);福建省教育厅A类科技项目(No.JA10164)~~

摘　　要：目的:探讨围绝经期综合征肝郁病理与雌性激素之间的相关性。方法:采用随机数字表法,选取50例健康妇女作为对照组,150例围绝经期综合征患者作为观察组,采用证素辨证进行肝郁病理改变分析,观察肝郁病理与雌性激素水平之间的关系。结果:围绝经期综合征肝郁积分,观察组明显高于对照组(P<0.01);肝郁病理改变分布情况,观察组与对照组有明显差异(P<0.01);月经紊乱和绝经的肝郁病理改变,与FSH、LH、FSH/LH呈正相关,与E2呈负相关。结论:肝郁病理是围绝经期综合征的核心病机之一,与FSH、LH、FSH/LH呈正相关,与E2水平变化呈负相关。Objective： Study interrelationship of liver depression and estrogen in perimenopausal syndrome. Methods： 150 cases of the perimenopausal syndrome were randomly observed, 50 healthy women as control. Using of syndrome elements differentiation, observed the relationship of liver depression and estrogen level. Results： Liver depression scores of perimenopausal syndrome, the observation groups were significantly heavier than the control group （P〈0.01）. Liver depression pathological change of perimenopausal syndrome, the observation groups were significantly heavier than the control group （P〈0.01）. It was liver depression positively correlated with FSH, LH and FSH/LH, and negatively correlated with E2, in perimenopausal syndrome menstrual disorders and menopausal. Conclusion： Liver depression is one of the cores of pathogenesisa in the perimenopansal syndrome, which is positively correlated with FSH, LH and FSH/LH, and negatively correlated with E2 Levels.

关 键 词：围绝经期综合征 肝郁病理 雌性激素 

分 类 号：R271.9[医药卫生—中西医结合]