Green spermatozoa illuminate a 30-year-old model： sperm-egg adhesion involves intra-acrosomal proteins  

作　　者：Steve Tardif 

机构地区：[1]Reproductive and Developmental Biology Group, Centrefor Oncology and Molecular Medicine, Division ofMedical Sciences, Ninewells Hospital, University ofDundee, Dundee, Scotland DD1 9SY, UK

出　　处：《Asian Journal of Andrology》2011年第5期665-666,共2页亚洲男性学杂志（英文版）

摘　　要：Fertilisation in mammals involves many synchronized steps including spermegg adhesion. Prior to sperm-oolemma fusion, spermatozoa need to undergo the acrosome reaction （AR） or exocytosis. The universal belief, for many years, has been that the AR was initiated upon binding to the zona pellucida （ZP）. As such acrosomal proteins were not thought to be involved in the primary contact with the ZP. These proteins were only suggested to be biologically relevant once the sperm were attached to the ZP and during subsequent events. However,Fertilisation in mammals involves many synchronized steps including spermegg adhesion. Prior to sperm-oolemma fusion, spermatozoa need to undergo the acrosome reaction （AR） or exocytosis. The universal belief, for many years, has been that the AR was initiated upon binding to the zona pellucida （ZP）. As such acrosomal proteins were not thought to be involved in the primary contact with the ZP. These proteins were only suggested to be biologically relevant once the sperm were attached to the ZP and during subsequent events. However,

分 类 号：Q492.6[生物学—生理学] Q51