高血压病合并颈动脉硬化中医证型研究  

Clinical Study on TCM Syndromes of Hypertension with Carotid Atherosclerosis

作　　者：黄琳[1] 史红秀[1] 黄汉超[1] 吴永刚[1] 

机构地区：[1]广东省第二中医院,广东广州510095

出　　处：《中国中医药信息杂志》2011年第9期23-25,共3页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：广东省科技厅立项课题(2008B060600071)

摘　　要：目的探讨临床上高血压病合并颈动脉粥样硬化的中医证型。方法运用四诊方法收集150例高血压病合并颈动脉硬化患者的病史资料、客观指标数据,根据颈动脉粥样硬化情况分为正常组、IMT增厚组和斑块组,并参照《中药新药临床研究指导原则(试行)》等分别对其进行辨证,得出辨证结论。结果中医证型中,气虚痰瘀型的斑块阳性率最高,达81.13%;气虚血瘀型次之,占59.52%;而气虚痰浊和痰热型的斑块阳性率最低,均为33.33%。颈动脉内膜中层增厚时以气虚血瘀为主证,而颈动脉粥样斑块形成时以气虚痰瘀为主证。结论高血压病合并颈动脉粥样硬化患者中气虚痰瘀证和气虚血瘀证为最主要的证型,其次为气滞血瘀证、气虚痰浊证、阴虚证和痰热证。Objective To discuss TCM syndrome type of hypertension with carotid atherosclerosis. Methods Four diagnostic methods were used to collect information of 150 patient＇s medical history and objective indicator data. The patients were divided into normal group, IMT thickness group and plaque group according to the situation of carotid atherosclerosis, and with reference to guidelines for new drug clinical research of Chinese medicine （Trial）, their syndromes were drawn. Results Plaque positive rate in type of qi deficiency and phlegm-stasis syndrome was up to 81.13%, qi deficiency and blood stasis syndrome accounted for 59.52%, while the qi deficiency and phlegm turbidity syndrome and phlegm-heat syndrome was 33.33% respectively. Carotid artery IMT thickening is mainly of qi and blood stasis syndrome, while carotid atherosclerotic plaque formation is mainly of qi deficiency and phlegm-stasis syndrome. Conclusion Qi deficiency and phlegm-stasis syndrome, qi deficiency and blood stasis syndrome were the major syndromes of patients with hypertension and carotid atherosclerosis, followed by qi stagnation and blood stasis syndrome, qi deficiency and phlegm turbidity syndrome, yin deficiency syndrome, phlegm-heat syndrome.

关 键 词：高血压病 颈动脉粥样硬化 中医证型 颈动脉内膜中层厚度 斑块 

分 类 号：R259.441[医药卫生—中西医结合]