氯诺昔康超前镇痛用于腹腔镜下胆囊切除的应用  

Application of lornoxicam for preemptive analgesia after laparoscopic cholecystectomy

作　　者：安宁[1] 

机构地区：[1]四川省崇州市人民医院麻醉科,611230

出　　处：《齐齐哈尔医学院学报》2011年第14期2258-2259,共2页Journal of Qiqihar Medical University

摘　　要：目的探讨非甾体类抗炎药氯诺昔康超前镇痛对腹腔镜胆囊切除术的安全性及效果。方法 76例腹腔镜胆囊切除术患者被纳入研究,按入院先后顺序随机均分为观察组及对照组(每组38例)。观察组气管插管前20 min静脉预先注射氯诺昔康16 mg;对照组气管插管前20 min静脉注射牛理盐水4 ml。观察患者术后2、4、8、12、24 h各时点的观察并记录两组病人杜冷丁使用情况和不良反应,以视觉模拟评分(VAS)评价其镇痛效果,以舒适评分标准(BCS)判定病人满意程度。结果每个时点观察组的杜冷丁使用例数及VSA评分明显低于对照组,而总体满意度也显著高于对照组(P<0.05),未见明显不良反应。结论氯诺昔康超前镇痛对腹腔镜胆囊切除术的术后镇痛效果确切,无明显不良反应,有推广应用价值。Objective To explore the efficacy and safety of preemptive analgesia with non-steroidal anti-inflammatory drug lornoxicam for laparoscopic cholecystectomy. Methods 76 cases of laparoscopic cholecystectomy,according to the order of admission were randomly divided into observation and the control groups（n = 38）.Endotracheal intubation 20min,intravenous,pre-observation group were injected lornoxicam 16mg,the control group was injected with normal saline 4ml.Two groups were compared after 2,4,8,12,24 h each time point pethidine usage and adverse reactions to visual analog scale（VAS） evaluation of its analgesic effect,a comfortable standard score（BCS） to determine patient satisfaction.Results Each point in time,the observation group was significantly lower than the control group for the VSA score and number of cases using pethidine.However,overall satisfaction was significantly higher（P0.05）,no significant adverse reactions.Conclusions Lornoxicam preemptive analgesia on laparoscopic cholecystectomy exact analgesic effect,no significant adverse reactions have application value.

关 键 词：腹腔镜 胆囊切除术 氯诺昔康 超前镇痛 

分 类 号：R971.1[医药卫生—药品]