神经内分泌-免疫调节网络参与腮腺炎病毒性脑炎合并胰腺炎分析  

Analysis on neuroendocrine-immunoregulatory network involved in mumps,viral encephalitis combined with pancreatitis

作　　者：秦越[1] 张舒岩[2] 杨立彬[3] 张现娥[3] 

机构地区：[1]吉林省吉林中西医结合医院,132012 [2]吉林大学第一医院急救医学 [3]吉林大学第一医院儿科

出　　处：《中国妇幼保健》2011年第25期3896-3897,共2页Maternal and Child Health Care of China

基　　金：全国第四十届博士后科学基金项目〔20060400893〕

摘　　要：目的:探讨神经内分泌-免疫调节网络在儿童腮腺炎病毒性脑炎合并胰腺炎中的作用及意义。方法:对23例腮腺炎病毒性脑炎合并胰腺炎患儿临床病例分析并进行血清及脑脊液中IL-1、TNF-α的水平检测。结果:患儿血清及脑脊液中IL-1、TNF-α的水平明显高于对照组。结论:神经-免疫-内分泌系统参与儿童腮腺炎病毒性脑炎合并胰腺炎的病理过程,为临床上早期给予大剂量激素治疗提供了有力证据。Objective ： To explore the effect and significance of neuroendocrine - immunoregulatory network in children with mumps, viral encephalitis combined with pancreatitis. Methods ： The clinical data of 23 children with mumps, viral encephalitis combined with pancreatitis were analyzed, the levels of IL - 1 and TNF - a in serum and eerebrospinal fluid were detected. Results： The levels of IL - 1 and TNF - a in serum and cerebrospinal fluid of children with mumps, viral encephalitis combined with panereatitis were significantly higher than those in control group. Conclusion ： Nerval - immune - endocrine system participates in the pathological process of mumps, viral encephalitis combined with pancreatitis in children, which provides a strong evidence for large - dosage hormonal therapy during the early clinical stage.

关 键 词：腮腺炎病毒性脑炎 胰腺炎 神经内分泌-免疫调节网络 IL-1 TNF-A 

分 类 号：R512.3[医药卫生—内科学]