Gd-DTPA对前列腺3T氢质子波谱影响的初步研究  

Effects of Gd - DTPA on Prostate ^1H - MR Spectroscopy

作　　者：杨春[1] 徐凯[1] 郑骏年[2] 许倩[1] 马红[1] 荣玉涛[1] 

机构地区：[1]徐州医学院附属医院放射科 [2]徐州医学院肿瘤生物治疗重点实验室

出　　处：《中国医学计算机成像杂志》2011年第4期332-334,共3页Chinese Computed Medical Imaging

摘　　要：目的:用高场MR仪研究对比剂(Gd-DTPA)是否会影响前列腺氢质子MR波谱(1H-MRS)的线宽(LW)、抑水率(WS%)及谱线质量。方法:对连续30例行前列腺MR波谱检查的患者分别于增强扫描前、后行1H-MRS检查,比较扫描前、后两次LW、WS%及谱线质量。结果:增强后LW(14.41±1.78)较增强前(12.25±1.36)增高(P<0.05)。增强后WS%(97.75±0.45)与增强前(97.50±0.25)比较,其变化无统计学意义(P>0.05)。增强后的谱线质量降低(P<0.05)。结论:Gd-DTPA影响前列腺1H-MRS的LW及谱线质量。Purpose： Using high field MR system to study whether the result of ^1H - MR spectroscopy （MRS） could be influenced by Gd- DTPA. Methods： ^1 H - MRS examinations were taken before and after administration of Gd - DTPA on 30 cases. Line width （LW）, water suppression （WS%） and spectroscopy quality before and after administration of Gd - DTPA were compared. Results： iW of spectroscopy after administration of Gd- DTPA （14.41 ± 1.78） was increased than before （12.25 ± 1.36） （P 〈 0.05）. WS% before and after administration of Gd - DTPA showed no statistical difference（P 〉 0.05） . Spectroscopy quality of ^1H - MRS after administration of Gd - DTPA was decreased than before（P 〈 0.05） . Conclusion： Gd- DTPA can change the LW and spectroscopy quality of prostate ^1H- MRS at 3 T.

关 键 词：前列腺 磁共振波谱 钆喷替酸葡甲胺 

分 类 号：R445.2[医药卫生—影像医学与核医学]