不同加工方法对亳白芍中芍药苷及水溶性浸出物含量的影响  

Study on the Effects of Different Methods on the Content of Paeoniflorin and Water-soluble Extract in Radix Paeoniae Alba in Bozhou

作　　者：王甫成[1,2] 时维静[3] 汪翠妮[3] 

机构地区：[1]亳州职业技术学院,安徽亳州236800 [2]山东中医药大学,济南205355 [3]安徽科技学院,安徽蚌埠233100

出　　处：《中国实验方剂学杂志》2011年第18期75-78,共4页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：安徽省高等学校省级优秀青年人才基金项目(2010SQRL213);安徽省高校省级自然科学研究项目(KJ2010B418)

摘　　要：目的:通过比较不同加工方法对亳白芍中芍药苷和水溶性浸出物含量的影响,为稳定亳白芍的产地加工工艺积累资料。方法:以芍药苷和水溶性浸出物含量为指标,采用高效液相色谱法和《中国药典》2010年版一部附录ⅩA水溶性浸出物测定法,测定经不同方法加工的亳白芍药材中芍药苷和水溶性浸出物的含量,考察不同加工方法对亳白芍中芍药苷和水溶性浸出物含量的影响。结果:不同加工方法亳白芍中芍药苷和水溶性浸出物的含量以直接晒干含量为最高,达到3.87%;煮后刮皮晒干者次之;生刮皮后煮晒干者含量最低。结论:以芍药苷和水溶性浸出物含量为主要评价指标,不同加工方法对亳白芍中芍药苷和水溶性浸出物含量有较大影响,直接晒干亳白芍中两种指标成分含量最高。Objective：To accumulate data to stabilize the processing technology of Radix Paeoniae Alba in Bozhou by comparing the effects of different processing methods on the content of the paeoniflorin and the water-soluble extract in Radix Paeoniae Alba in Bozhou.Method：With the paeoniflorin and the water-soluble extract as criteria,the content of the paeoniflorin and the water-soluble extract in Radix Paeoniae Alba in Bozhou with different processing methods are determined by HPLC and the methods of water-soluble extract determination included in Appendix Ⅹ A of China Pharmacopeia 2010（vol.Ⅰ）.The effects of different processing methods on the content of the paeoniflorin and the water-soluble extract in Radix Paeoniae Alba in Bozhou are investigated in the experiment.Result：With regard to the content of the paeoniflorin and the water-soluble extract in Radix Paeoniae Alba in Bozhou with different processing methods,the content of the method of directly drying is higher up to 3.87% than that of the method of scraping and drying after boiling.The content of this method of boiling and drying after scraping is the lowest.Conclusion：The different methods have different effects on the content of the paeoniflorin and the water-soluble extract in Radix Paeoniae Alba in Bozhou,and the highest content is obtained by the method of directly drying.

关 键 词：亳白芍 芍药苷 水溶性浸出物 加工方法 

分 类 号：R284.1[医药卫生—中药学]