清瘟解毒片的质量标准研究  

Study on Quality Standard of Qingwen Jiedu Tablets

作　　者：赵江红[1] 高超旭 郭建功 张东彬 

机构地区：[1]河南省安阳市食品药品检验所,河南安阳455000 [2]郑州福瑞堂制药有限公司,郑州450001 [3]郑州豫密药业股份有限公司,郑州452392

出　　处：《中国实验方剂学杂志》2011年第18期95-97,共3页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：目的:研究和修订清瘟解毒片质量标准。方法:采用薄层色谱法(TLC)对清瘟解毒片中的葛根、赤芍、白芷进行定性鉴别;采用HPLC法测定黄芩苷的含量。结果:葛根、赤芍、白芷的TLC鉴别法专属性强,简单可行。HPLC含量测定,黄芩苷在21～1.68 mg.L-1与峰面积成良好的线性关系(r=0.999 9,n=5);黄芩苷的回收率为97.49%,RSD 0.32%。结论:该法能更为有效的控制清瘟解毒片的质量。Objective：Study and revise the quality standard of Qingwen Jiedu tablets.Method：Pueraria radix,Paeoniae radix rubra,Angelicae dahuricae radix in Qingwen Jiedu tablets were identified by TLC method and the content of baicalin was determined by HPLC.Result：TLC identification method for Pueraria radix,Paeoniae radix rubra,Angelicae dahuricae radix was simple and feasible with strong specificity.Baicalin content was linear in the range of 21-168 mg·L-1,the recovery was 97.49%,RSD 0.32%.Conclusion：The method can effectively control the quality of Qingwen Jiedu tablets.

关 键 词：清瘟解毒片 薄层色谱法 高效液相色谱法 质量标准 

分 类 号：R284.1[医药卫生—中药学]