龙藤生血丸治疗肾阳虚型慢性再生障碍性贫血  

Clinical Study on Treatment of Shenyangxu of Chronic Aplastic Anemia with Longteng Shengxue Pill

作　　者：刘清池[1] 李建英[1] 马亚辉[1] 梁春耕[1] 张慧敏[1] 马传宝[1] 庞宇慧[1] 王荣孝[1] 吴晓然[1] 熊建军[1] 

机构地区：[1]石家庄平安医院血液科,石家庄050021

出　　处：《中国实验方剂学杂志》2011年第18期256-259,共4页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：目的:观察龙藤生血丸治疗肾阳虚型慢性再生障碍性贫血的临床疗效。方法:用前瞻性队列研究的方法将纳入研究的病例分为治疗组与对照组,分别用龙藤升血丸(8 g,3次/d,口服)和环孢菌素(2～3 mg.kg-1/d,口服)治疗,用药6个月以上,观察疗效及不良反应。结果:治疗组基本治愈2例、缓解17例、明显进步23例,总有效率70.0%,明显高于对照组的45.0%(P<0.05)。治疗组骨髓有核细胞增生程度明显改善。治疗组不良反应轻微,而且明显少于对照组(P<0.01)。结论:龙藤生血丸治疗慢性再生障碍性贫血疗效好,无明显毒副作用,值得临床推广应用。Objective：To observe the efficacy of shenyangxu of chronic aplastic anemia treatment with Longteng Shengxue pill.Method：A prospective cohort study,included in the study were divided into treatment group and control group,respectively treatment with Longteng Shengxue pill and cyclosporine,the efficacy and adverse effects were observed.Result：The basic cure 2 patients,remission in 17 cases,significant improvement in 23 cases,total effective rate 70.0%,significantly higher than the 45.0%（P0.05）.Degree of proliferation of Bone marrow nucleated cells was significantly improved in the treatment group.Adverse reactions are mild in the treatment group,and significantly less than the control group（P0.01）.Conclusion：The chronic aplastic anemia treatment with Longteng Shengxue pill is effective,no obvious side effects,and is worthy of clinical application.

关 键 词：再生障碍性贫血 队列研究 龙藤生血丸 

分 类 号：R287[医药卫生—中药学]