解毒活血法对急性冠脉综合征患者PCI术后HSP60表达的影响  

Effect of Detoxication and Activating Blood Circulation to Eliminate Phleg in Chinese Medicine Method on HSP 60 in Acute Conoary Syndrome Patients After PCI

作　　者：郭秋影[1] 宫丽鸿[2] 赵静[1] 高峰[1] 汪雨静[1] 黄欢[1] 

机构地区：[1]辽宁中医药大学,辽宁沈阳110032 [2]辽宁中医药大学附属医院,辽宁沈阳110032

出　　处：《辽宁中医杂志》2011年第9期1820-1822,共3页Liaoning Journal of Traditional Chinese Medicine

基　　金：辽宁省科学技术重大项目(2008225010_22);沈阳市科委资助项目(1071215)

摘　　要：目的:观察解毒活血法对急性冠脉综合征患者PCI术后HSP 60表达的影响。方法:将50例急性冠脉综合征PCI术后患者随机分组,对照组25例予常规西药,治疗组25例在常规西药治疗基础上加用解毒活血中药,检测治疗前后两组血清HSP 60表达水平。结果:与对照组相比,治疗组血清HSP 60表达水平显著降低。结论:解毒活血法能明显降低急性冠脉综合征患者PCI术后血清HSP 60表达水平,表明解毒活血中药能抑制对PCI术后炎性反应,对ACS的诊断、预后判断有一定的价值。Objective：To observe the effect of detoxication and activating blood circulation to eliminate phleg in Chinese medicine method on HSP 60 in acute coronary syndrome patients after PCI. Methods：50 acute coronary syndrome patients after PCI were randomly divided into treatment group（25 patients） and control group （25 patients）. The treatment group was treated with general medicine and Chinese traditional medicine. The control group was treated with general medicine . Then measure the level of HSP 60 . Results ： Contrary to the control group , the level of the HSP 60 of the treatment group were singificant lower. Conclusion ： The detoxieation and activating blood circulation of Chinese traditional medicine can evidently reduce the level of HSP 60 in acute coronary syndrome patients after PCl. It indicates the detoxication and activating blood circulation of Chinese traditional medicine can inhibit inflammation alter PCI,the value of it in the diagnosis and prognosis judgment of ACS has been fuund.

关 键 词：热休克蛋白60 经皮冠状动脉介入治疗(PCI) 急性冠脉综合征(ACS) 解毒 活血 

分 类 号：R541.4[医药卫生—心血管疾病]