蛇鳞草化学成分研究  

Chemical constituents in herb of Pronephrium triphyllum

作　　者：钟希文[1,2] 张文霞[3] 卢海啸[3] 高幼衡[3] 

机构地区：[1]广州中医药大学附属中山市中医院,广东中山528400 [2]中山市中医药研究所,广东中山528400 [3]广州中医药大学,广东广州510006

出　　处：《中草药》2011年第9期1673-1677,共5页Chinese Traditional and Herbal Drugs

基　　金：中山市科技计划立项项目(20071A036)

摘　　要：目的研究蛇鳞草Pronephrium triphyllum的化学成分。方法利用硅胶柱色谱及Sephadex LH-20柱色谱进行分离纯化,并通过理化性质和波谱数据鉴定化合物结构。结果从蛇鳞草中分离得到6个化合物,分别鉴定为(2S,4R)-4′-methoxy-8-methyl-[(4,2″)(11,2′′′)]-dioxidoflavan-5,7-di-O-β-D-glucopyranoside(蛇鳞草苷A,1)、正丁基-β-D-吡喃果糖苷(2)、三羽新月蕨苷A(3)、6,7-二羟基香豆素(4)、胡萝卜苷(5)、β-谷甾醇(6)。结论化合物1为新化合物,命名为蛇鳞草苷A。化合物2和4为首次从该属植物中分离得到,除化合物3外,其余化合物均首次从该植物中得到。Objective To study the chemical constituents in herb of Pronephrium triphyllum.Methods The chemical constituents were isolated and purified with silica gel and Sephadex LH-20 column chromatography.Their structures were identified by spectral data and physicochemical properties.Results Six compounds were isolated and identified as（2S,4R）-4′-methoxy-8-methyl-[（4,2″）（11,2′′′）]-dioxidoflavan-5,7-di-O-β-D-glucopyranoside（shelincaoide A,1）,n-butyl-β-D-fructopyranoside（2）,triphyllin A（3）,6,7-dihydroxycomnarin（4）,daucosterol（5）,and β-sitosterol（6）,respectively.Conclusion Compound 1 is a new compound named shelincaoide A.Compounds 2 and 4 are firstly isolated from the plants of Pronephrium Presl.and all compounds except 3 are obtained from P.triphyllum for the first time.

关 键 词：蛇鳞草 蛇鳞草苷A 正丁基-β-D-吡喃果糖苷 三羽新月蕨苷A 6 7-二羟基香豆素 

分 类 号：R284.1[医药卫生—中药学]