微波辐射下过氧化氢氧化法合成对羧基苯磺酰胺  

Synthesis of p-Carboxy-Benzenesulfonamide by Oxidization of p-Toluenesulfonamide with Hydrogen Peroxide Under Microwave Irradiation

作　　者：谢建英[1] 黄甫[1] 

机构地区：[1]广东海洋大学理学院,广东湛江524088

出　　处：《石油化工》2011年第9期997-999,共3页Petrochemical Technology

基　　金：广东省科技计划项目资助(2010B010900036)

摘　　要：在微波辐射下,进行了以H_2O_2为氧化剂氧化对甲基苯磺酰胺合成对羧基苯磺酰胺的研究;采用正交实验考察了辐射功率、辐射时间、n(对甲基苯磺酰胺):n(H_2O_2)对对羧基苯磺酰胺收率的影响,并采用FTIR技术对产物的结构进行表征。实验结果表明,反应条件对对羧基苯磺酰胺收率影响显著性的顺序为:辐射功率>辐射时间>n(对甲基苯磺酰胺):n(H_2O_2);最佳的反应条件为:n(对甲基苯磺酰胺):n(H_2O_2)=1:2.2、辐射功率560 w、辐射时间7 min,在此条件下对羧基苯磺酰胺的收率可达67.5%以上,且最佳合成条件具有可再现性。p-Carboxy-benzenesulfonamide was synthesized through oxidation reaction of p-toluene- sulfonamide with hydrogen peroxide under microwave irradiation. The effects of irradiation power, irradiation time and mole ratio of p-toluenesulfonamide to hydrogen peroxide on p-carboxybenzene- sulfonamide yield were studied by orthogonal experimental design. The product was characterized by means of FTIR.

关 键 词：对羧基苯磺酰胺 对甲基苯磺酰胺 过氧化氢 氧化反应 微波辐射 

分 类 号：TQ247.57[化学工程—有机化工]