基于1,8-萘酰亚胺功能团的Hg^(2+)荧光分子探针的合成与性能  

Preparation and performance of Hg^(2+) ion based on 1,8-naphthalimide fluorophore

作　　者：朱西挺[1] 詹文毅[1] 张其平[1] 吴学朋[2] 雷武[2] 夏明珠[2] 王风云[2] 

机构地区：[1]南通大学化学化工学院,江苏南通226007 [2]南京理工大学工业化学研究所,江苏南京210094

出　　处：《化学试剂》2011年第9期833-836,845,共5页Chemical Reagents

基　　金：国家自然科学基金资助项目(20906052);江苏省南通市科技基金资助项目(K2008023);南通大学产学研项目(09C003)

摘　　要：以4-溴-1,8-萘酐和正丁胺为原料,合成了含有1,8-萘酰亚胺官能团的汞离子荧光分子探针4-二(2-羟乙基氨基)-乙氨基-N-n-丁基-1,8-萘酰亚胺(FP)。采用红外光谱、质谱及核磁共振氢谱等测试技术对产物进行了结构表征。考察了Cd2+、Hg2+、Na+、Pb2+、Co2+、Mg2+、Ca2+、Fe3+、Cu2+离子对该化合物荧光发射光谱的影响,结果表明Hg2+离子能使FP荧光显著增强。并探讨了荧光机理。结合其结构特点,认为FP是可逆的、灵敏的汞离子荧光探针,能成功应用于汞离子的检测。4-Bis（2-hydroxyethylamino）ethylamino）-N-n-butyl-1,8-naphthalimide（FP）,a novel water soluble fluorescent molecular probe,was synthesized by using 4-bromo-1,8-naphthalic anhydride and n-butane amine as starting materials.The structure was characterized by IR,MS and 1HNMR.The influence of the different metal cations,such as Cd2＋,Na＋,Pb2＋,Co2＋,Mg2＋,Ca2＋,Fe3＋,Cu2＋ and Hg2＋ ions on the fluorescent spectra of FP was investigated.The results indicated that the fluorescence intensity of FP could be greatly increased by Hg2＋ ion.The fluorescence mechanism was discussed.FP was a reversible and sensitive mercury ion fluorescent probe and could be successfully applied to the detection of mercury ion.

关 键 词：1 8-萘酐 合成 汞离子荧光探针 荧光光谱 

分 类 号：O657.3[理学—分析化学]