补肾活血化痰法治疗多囊卵巢综合征胰岛素抵抗的临床研究  

Clinical Research on Kidney-tonifying Blood-activating and Sputum-Eliminating Therapy for the Treatment of Polycystic Ovary Syndrome(PCOS) with Insulin Resistance(IR)

作　　者：孙维峰[1] 梁静[1] 张娴娴[1] 冯书梅[1] 

机构地区：[1]广州军区广州总医院中医科,广东广州510010

出　　处：《中华中医药学刊》2011年第9期2018-2020,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：广东省中医药局资助项目(2007204)

摘　　要：目的:观察补肾活血化痰中药治疗多囊卵巢综合征胰岛素抵抗的临床疗效。方法:将符合纳入标准38例患者随机分成两组,西药组口服二甲双胍,中药组用补肾活血化痰法组方多囊调经汤,分别观察两组病例治疗前后临床疗效、双侧卵巢体积大小和卵泡数变化、血清性激素水平的变化。结果:中药组总有效率90.5%,妊娠率28.5%,西药组总有效率58.8%,妊娠率5.9%,两组比较有显著差异(P<0.01);治疗后两组血清LH值,T值,INS值明显降低,E2值升高,与治疗前比较有显著性差异(P<0.05);中药组治疗后B超双侧卵巢体积缩小、卵泡数减少,与治疗前比较有显著性差异(P<0.05),而西药组治疗后双侧卵巢体积及卵泡数与治疗前均无明显差异(P>0.05)。结论:补肾活血化痰中药治疗多囊卵巢综合征胰岛素抵抗具有良好的效果,其整体性和综合性的优势展示了良好的应用前景。Objective ： To investigate the clinical efficacy on Kidney - tonifying, Blood - activating and sputum - elimi- nating Therapy for the Treatment of Polycystic Ovary Syndrome with insulin resistance. Methods ： In the experiment, 38 P- COS patients were randomly allocated into 2 groups. In the Chinese herb group, the author treated 21 patients 3 periods of treatment with the therapy for tonifying kidney, promoting blood and eliminating sputum which was consociated to regu- late menstrual cycle. In the Western medicine group, the author treated 17 patients 3 period of treatment with Metformin. The author observed all the change of these patients, such as the change of their catamenia cycles and the change of their gestation. Results ： In the Chinese herb group and the gestation efficiency was 61.9% , the total efficiency of the patients was 90.5% ;in the Western medicine group the gestation efficiency was 5.9% and the total efficiency of the patients was 58.8% ; In the two groups,the T value,INS value,LH value of the serum increased clearly, and the E2 value reduced clearly（P 〈 0.05 ） ;Through 3 periods of treatment, the ovary became bigger and the ovum increased in the Chinese herb group（P 〈0.05）, but in the western medicine group these changes were not observable（ P 〉 0.05 ）. Conclusions： The decoction of tonifying kidney, promoting blood and eliminating sputum has a good effect in treating PCOS, and its will have a good prospect.

关 键 词：多囊卵巢综合征 补肾活血化痰法 胰岛素抵抗 

分 类 号：R711.75[医药卫生—妇产科学]