门冬氨酸鸟氨酸注射液抗肝性脑病的疗效观察  

Efficacy of ornithine aspartate for injection on hepatic encephalopathy

作　　者：赵丽 

机构地区：[1]辽宁省锦州市传染病医院药剂科,辽宁锦州121000

出　　处：《中国当代医药》2011年第24期76-77,共2页China Modern Medicine

摘　　要：目的:观察门冬氨酸-鸟氨酸治疗肝性脑病的临床疗效。方法:回顾性分析本院2008年3月～2010年12月收治入院的肝性脑病患者56例,将其随机分为两组,治疗组28例,对照组28例。对照组常规治疗,治疗组采用门冬氨酸-鸟氨酸治疗并测定患者治疗前、后血清氨的水平,观察其临床疗效。结果:肝性脑病患者血氨水平明显增加,且与肝性脑病病情程度相关,两组相比,差异具有统计学意义(P<0.05)。结论:门冬氨酸-鸟氨酸治疗后血氨含量下降程度和肝性脑病清醒时间明显优于对照组,门冬氨酸-鸟氨酸对肝性脑病具有明显疗效。Objective： To observe the ornithine aspartate for injection in the treatment of hepatic encephalopathy patients. Methods： 56 patients with hepatic encephalopathy in our hospital from March 2008 to December 2010 were admitted and were randomly divided into two groups, treatment group 28 cases, 28 patients in control group. The control group were given routine treatment, treatment group were given ornithine aspartate for injection. The serum ammonia level and clinical efficacy were measured before and after treatment. Results： The blood ammonia levels in patients with hepatic encephalopathy was significantly increased, and associated with the severity of hepatic encephalopathy, there was significant differences between the two groups （P〈0.05）. Conclusion： The serum ammonia levels and hepatic encephalopathy recovery time were better than the control group after the treatment. Ornithine aspartate for injection has significant effect on hepatic encephalopathy.

关 键 词：肝性脑病 生命质量 门冬氨酸-鸟氨酸 疗效观察 

分 类 号：R977.4[医药卫生—药品]