植物油提取五味子木脂素工艺的研究  

Study on Extraction Process of Lignanoids from Schisandra chinesis(Turcz.) Baill by Vegetable Oil

作　　者：徐仲航[1] 金向群[2] 

机构地区：[1]东北师范大学附属中学,长春130021 [2]吉林大学药学院,长春130021

出　　处：《特产研究》2011年第3期41-43,共3页Special Wild Economic Animal and Plant Research

摘　　要：通过正交试验,探讨植物油提取五味子木脂素新工艺及其工艺条件,并采用高效液相色谱技术测定提取物五味子甲素及五味子乙素含量。结果表明,影响植物油提取的主要因素是植物油用量B、提取次数C、提取时间A,其最佳提取工艺组合为A3B3C2;水提取、醇提取、超临界提取和植物油提取得到的提取物中五味子甲素及五味子乙素总量分别为3.24mg、36.57mg、38.56mg和38.00mg,提取率分别为8.28%、93.1%、98.2%和96.8%。本研究确定了植物油提取五味子木脂素的新工艺;用新工艺提取得到的提取物中,五味子木脂素含量和提取率均较高;新工艺具有操作简便、无污染、条件温和等优点,对五味子的开发利用具有推广价值。To investigate a new technology for extraction of lignanoids by vegetable oil, and compare it with other methods. Optimized conditon with orthogonal design, we got the determination of schisandrin A and schisandrin B by High Performance Liquid Chromatography （HPLC）. The main factors that influenced extraction were the amount of oil B, extracting times C, extracting time A. The best extraction process was A3B3C2. Total amount of schisandrin A and schisandrin B by the technology of water extraction, alcohol extraction, SFE-CO2 extraction and vegetable oil extraction was 3.24mg, 36.57mg, 38.56mg and 38.00mg, and extraction rate was 8.28%, 93.1%, 98.2% and 96.8% respectively. Establishtion of optimal technological process for lignanoids extraction by vegetable extraction, which provide several advantages such as simple work-up procedure, environmental friendliness and milder conditions, performs further exploitation and utiliza- tion prospect for Schisandra.

关 键 词：五味子 木脂素 提取工艺 

分 类 号：R284.2[医药卫生—中药学]