2型糖尿病患者血清胆红素水平变化及意义  

Clinical significance of serum bilirubin levels in patients with type 2 diabetes mellitus

作　　者：沙立萍[1] 于晓莉[2] 雷红[1] 

机构地区：[1]宁夏医科大学附属医院,宁夏银川750004 [2]宁夏自治区人民医院,宁夏银川750021

出　　处：《宁夏医学杂志》2011年第9期854-855,共2页Ningxia Medical Journal

摘　　要：目的探讨2型糖尿病(T2DM)患者血清胆红素水平变化及临床意义。方法采用全自动生化分析仪分别对240例T2DM患者进行胆红素水平检测。结果糖化血红蛋白(HbA1c)增高者(166例,66.17%)总胆红素和直接胆红素水平低于糖化血红蛋白正常者(74例,30.83%)(P<0.05);糖尿病病程>1年者(126例)总胆红素和直接胆红素水平低于病程<1年者(74例,P<0.05)。结论检测2型糖尿病患者血清胆红素水平对预测评估病情及预后有一定临床价值。Objective To investigate variation and its clinical significance of levels of serum bilirubin（BIL） in patients with type 2 diabetes mellitus（T2DM）.Methods Automatic biochemical analyzer was used for measuring the levels of serum BIL in 240 patients.Results The levels of serum total BIL（TBIL） and indirect BIL（NDBIL） of T2DM patients with HbA1c6.5% were obviously lower than those in patients with HbA1c6.5%（P0.05）.The TBIL and NDBIL levels of the group with duration of diabetes over one year were significantly lower than those less than 1 year（P0.05）.Conclusion Detecting serum levels of bilirubin is of great significance to the clinical diagnosis and prognosis in patients with T2DM.

关 键 词：2型糖尿病 胆红素 

分 类 号：R587.1[医药卫生—内分泌]