噻托溴胺治疗稳定期COPD  

The observation of theraptutic effect of inspiring Tiotropium Bromide Powder in patients with COPD in stable stage

作　　者：于立萍[1] 巩法桃[1] 李凯述[1] 欧阳修河[1] 

机构地区：[1]滨州市人民医院呼吸科,山东滨州256610

出　　处：《临床肺科杂志》2011年第10期1526-1527,共2页Journal of Clinical Pulmonary Medicine

摘　　要：目的观察噻托嗅胺对稳定期慢性阻塞性肺疾病(COPD)患者的临床疗效。方法 40例稳定期COPD患者随机分成两组,实验组应用噻托嗅铵18 ug吸入,1次/天,对照组口服茶碱缓释片100 mg,2次/天.观察记录患者治疗前后肺功能、6min步行距离、生活质量评分。结果两组治疗后肺功能、临床症状等较治疗前均有好转,但实验组较对照组FEVl占预计值百分比明显增加,生活质量明显改善,6 min步行距离、临床症状明显改善。两组治疗前后各项指标比较,差异具有统计学意义(P<0.05或P<0.01)。结论长期规律吸入噻托溴胺可有效改善慢阻肺患者肺功能并缓解临床症状,提高患者的生活质量。Objective To observe the effects of inspiring Tiotropium Bromide Powder in patients with COPD in stable stage.Methods 40 patients with COPD in stable stage were randomly divided into two groups,the experimental group received inhaling of tiotropium 18 ug（qd）,and the control group received the small dosage thephylline slow release piece 100 mg（bid）.The outcomes measured included as the following：lung function,6 min walk distance,the quality of life.Results After treated,the lung function and the clinical symptom had the change for the better both in two groups,and the FEV1%pre,6 min walk distance and the clinical symptom were superior in experimental groups to control groups obviously,and the difference had statistics significance（P〈0.05 or P〈0.01）.Conclusions Long-term regularly persistent Tiotropium could improve the patient’s lung function and alleviate the clinical symptom effectively,and improves patients life quality.

关 键 词：噻托溴胺 慢性阻塞性肺疾病 茶碱缓释片 

分 类 号：R563.9[医药卫生—呼吸系统]