胆囊结石和胆囊切除术与结直肠癌的关系探讨  

The Relationship between =cholelithiasis and cholecystectomy and colorectal cancer

作　　者：苏位东[1] 

机构地区：[1]北京老年医院普外科,北京100095

出　　处：《临床和实验医学杂志》2011年第17期1343-1344,共2页Journal of Clinical and Experimental Medicine

摘　　要：目的研究胆囊切除术和胆囊结石与结直肠癌之间的关系。方法选取近4年经病理证实的结直肠癌患者282例做为结直肠癌组,选择同期在我院体检的330人做为健康对照组,对两组资料进行回顾性分析,对比观察两组的胆囊结石患病率、胆囊切除百分率,并对年龄、性别、发病部位等因素作分析。结果结直肠癌组282例中,胆囊结石患病率明显高于对照组,两组间比较差异有统计学意义(P<0.05)。两组在胆囊切除术的手术百分率上差异无统计学意义(P>0.05)。60岁以上结直肠癌患者的胆囊结石患病率较对照组显著增高,两组比较差异有统计学意义(P<0.05)。结直肠癌组中在肿瘤部位、性别等方面的差异无统计学意义(P>0.05)。结论胆囊结石是结直肠癌发病的高危因素。Objective To study the relationship between cholelithiasis, cholecystectomy and colorectal cancer. Methods Retrospectively, the incidence of cholelithiasis and choleeystectomy in 282 cases of colorectal cancer was compared with that of 330 cases of gastric cancer（ control group）. The patient age, sex and the location of the tumor were analyzed. Results Colorectal cancer group 282 examples, gallstones is obvi- ously higher than that of the cancer of the stomach, the percentage of stones through the percentage between the two groups was statistically signifi- cant comparative differences （ P 〈0.05 ）. Colorectal cancer and stomach cancer group in the surgery group cholecystectomy difference in percent- age was statistically significant （ P 〉 0.05）. More than 60 patients with colorectal cancer of the gallbladder disease incidence is stomach cancer group significantly higher, two groups of gallbladder disease percentage is statistically significant comparative differences （ P 〈 0.05 ）. Colorectal cancer with cystic and calculous, cystic resection in sex than a tumor site, the difference was not statistically significant （ P 〉 0.05 ）. Conclusion Choelithiasis increase the risk of colorectal cancer.

关 键 词：结肠直肠癌 胆囊结石 胆囊切除术 

分 类 号：R657.4[医药卫生—外科学]