丙泊酚复合瑞芬太尼或芬太尼用于无痛人流麻醉的疗效分析与评价  

The Comparison of Efficacy Propofol Combined with Remifentanil or Fentanyl in Painless Abortion

作　　者：何敏[1] 

机构地区：[1]四川省成都市锦江区妇幼保健院麻醉科,610016

出　　处：《临床合理用药杂志》2011年第06X期45-46,共2页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的比较瑞芬太尼或芬太尼复合丙泊酚麻醉在无痛人流术中的效果和安全性。方法选择200例ASAⅠ级拟行无痛人流术的患者,随机分为两组:芬太尼组和瑞芬太尼组,每组100例,观察麻醉和术中丙泊酚用量、生命体征、体动、呼吸抑制和术后苏醒时间、腹痛情况等。结果术中丙泊酚的总用量芬太尼组>瑞芬太尼组,芬太尼组血压下降明显。术后恢复时间瑞芬太尼组快;术中呼吸抑制瑞芬太尼组明显低于芬太尼组;芬太尼组与瑞芬太尼组在术后腹痛的发生方面差异无统计学意义。结论靶控输注瑞芬太尼麻醉比芬太尼更适用于无痛人流术,但仍需注意术中的呼吸管理。Objective Our aim was to compare with the efficacy and safety of propofol combined with fentanyl or remifentanil on anesthesia for induced abortion. Methods 200 patients undergoing painless induced abortion were randomly di vided into two groups ： the fentanyl group and remifentanil group, each group has 100 patients. Several factors were observed in- cluding the dose of propofol, vital signs, body movement, respiratory depression, recovery time after anesthesia and postopera- tive bellyache. Results The total doses of propofol during anesthesia in the fentanyl group was greater than that in the remifen- tanil group. Compared with remifentanil anesthesia induction, the blood pressure of fentanyl group decreased significantly. The recovered time in the remifentanil group was quicker than that in the fentanyl group. Compared with remifentanil grouP, the rate of respiratory depression in fentanyl group was increased significantly. And the incidence of postoperative bellyache was no signifi- cant in the fentanyl group and remifentanil group. Conclusion Target controlled infusion of remifentaniI used in painless in- duced abortion had much more advantages than fentanyl, but attention must also be paid to respiratory management.

关 键 词：丙泊酚 芬太尼 瑞芬太尼 无痛人流 

分 类 号：R614[医药卫生—麻醉学]